Wheeler A G, Baird D T, Land R B, Scaramuzzi R J
J Reprod Fertil. 1977 Nov;51(2):427-32. doi: 10.1530/jrf.0.0510427.
Ewes with cervical ovarian autotransplants were studied after PGF-2alpha-induced luteal regression in November and February (mid- and late-breeding season) and June (anoestrum). Progesteron and oestradiol-17beta secretion rates and LH concentrations were determined in serial ovarian venous blood samples and the ewes were frequently tested for oestrus. All 4 ewes in November and 3 of the 4 ewes in February exhibited oestrus and endocrine changes indicative of ovulation. The remaining ewe in February and the three ewes in June failed to show elevated oestradiol-17beta secretion rates after luteal regression, indicating the absence of follicles in the final stages of maturation. The preovulatory rise in the oestradiol-17beta secretion rate, the LH surge and the display of oestrus all occurred earlier, with respect to the PGF-2alpha infusion, in November than in February, suggesting a greater stimulation of folliculogenesis, and therefore a greater availability of maturing follicles, in November than in February.
对接受子宫颈卵巢自体移植的母羊进行了研究，分别在11月和2月（繁殖季节中期和后期）以及6月（乏情期）给予PGF-2α诱导黄体退化后进行观察。通过连续采集卵巢静脉血样测定孕酮、雌二醇-17β分泌率和促黄体生成素（LH）浓度，并频繁检测母羊是否发情。11月的所有4只母羊以及2月的4只母羊中的3只表现出发情以及表明排卵的内分泌变化。2月剩下的1只母羊和6月的3只母羊在黄体退化后未出现雌二醇-17β分泌率升高，表明在成熟的最后阶段没有卵泡。就PGF-2α注入而言，11月雌二醇-17β分泌率的排卵前升高、LH激增和发情表现均比2月出现得更早，这表明11月比2月对卵泡生成的刺激更大，因此成熟卵泡的可用性更高。
