• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

On the nature of a transport alteration determining resistance to amethopterin in the L1210 leukemia.

作者信息

Sirotnak F M, Kurita S, Hutchison D J

出版信息

Cancer Res. 1968 Jan;28(1):75-80.

PMID:5635374
Abstract
摘要

相似文献

1
On the nature of a transport alteration determining resistance to amethopterin in the L1210 leukemia.
Cancer Res. 1968 Jan;28(1):75-80.
2
Comparative studies on the transport of aminopterin, methotrexate, and methasquin by the L1210 leukemia cell.L1210白血病细胞对氨基蝶呤、甲氨蝶呤和甲喹酮转运的比较研究。
Cancer Res. 1972 Oct;32(10):2120-6.
3
Amethopterin transport in Ehrlich ascites carcinoma and L1210 cells.氨甲蝶呤在艾氏腹水癌和L1210细胞中的转运。
Cancer Res. 1967 Sep;27(9):1539-43.
4
Sequential biochemical alteration to antifolate resistance in L1210 leukaemia.L1210白血病中抗叶酸耐药的序贯生化改变。
Nature. 1967 Dec 23;216(5121):1236-7. doi: 10.1038/2161236a0.
5
Differential cell permeability and the basis for selective activity of methotrexate during therapy of the L1210 leukemia.L1210白血病治疗期间细胞通透性差异及甲氨蝶呤选择性活性的基础。
Cancer Res. 1973 Jun;33(6):1290-4.
6
A comparison of 4-amino-4-deoxy-N10-methylpteroic acid and methotrexate transport by mouse leukemia cells.
Mol Pharmacol. 1969 Jan;5(1):21-5.
7
Relative frequency and kinetic properties of transport-defective phenotypes among methotrexate-resistant L1210 clonal cell lines derived in vivo.体内衍生的甲氨蝶呤抗性L1210克隆细胞系中转运缺陷表型的相对频率和动力学特性。
Cancer Res. 1981 Nov;41(11 Pt 1):4447-52.
8
Therapeutic relevance of differences in the structural specificity of the transport systems for folate analogs in L1210 tumor cells and in isolated murine intestinal epithelial cells.
Cancer Res. 1977 Dec;37(12):4297-303.
9
Effect of modification of plasma membrane fatty acid composition on fluidity and methotrexate transport in L1210 murine leukemia cells.
Cancer Res. 1979 May;39(5):1726-32.
10
The intracellular concentration dependence of antifolate inhibition of DNA synthesis in L1210 leukemia cells.抗叶酸药物对L1210白血病细胞DNA合成抑制作用的细胞内浓度依赖性
Cancer Res. 1974 Dec;34(12):332-40.

引用本文的文献

1
Albumin-Methotrexate Prodrug Analogues That Undergo Intracellular Reactivation Following Entrance into Cancerous Glioma Cells.进入恶性胶质瘤细胞后经历细胞内再活化的白蛋白 - 甲氨蝶呤前药类似物。
Pharmaceutics. 2021 Dec 28;14(1):71. doi: 10.3390/pharmaceutics14010071.
2
Biology of the major facilitative folate transporters SLC19A1 and SLC46A1.主要易化型叶酸转运蛋白SLC19A1和SLC46A1的生物学特性
Curr Top Membr. 2014;73:175-204. doi: 10.1016/B978-0-12-800223-0.00004-9.
3
Structure and function of the reduced folate carrier a paradigm of a major facilitator superfamily mammalian nutrient transporter.
还原型叶酸载体的结构与功能——主要易化子超家族哺乳动物营养转运体的范例
Vitam Horm. 2008;79:145-84. doi: 10.1016/S0083-6729(08)00405-6.
4
Bioautographic visualization of dihydrofolate reductase in enzyme overproducing BHK mutants.
Biochem Genet. 1980 Feb;18(1-2):199-206. doi: 10.1007/BF00504369.
5
Collateral sensitivity of a methotrexate-resistant L1210 cell line to the vinca alkaloids.甲氨蝶呤耐药L1210细胞系对长春花生物碱的 collateral敏感性 。(注:这里collateral根据语境可能不太好准确翻译,或许是“旁系”之类的意思,但直接保留英文更合适,因为不确定准确含义)
Cancer Chemother Pharmacol. 1984;13(1):43-6. doi: 10.1007/BF00401446.
6
Isolation and expression of an altered mouse dihydrofolate reductase cDNA.一种改变的小鼠二氢叶酸还原酶cDNA的分离与表达
Proc Natl Acad Sci U S A. 1983 May;80(9):2495-9. doi: 10.1073/pnas.80.9.2495.
7
Concentration and pH dependent steady-state volume of distribution of methotrexate estimated by a simple physiologically based method.
J Pharmacokinet Biopharm. 1984 Dec;12(6):597-610. doi: 10.1007/BF01059555.
8
Overproduction of dihydrofolate reductase and gene amplification in methotrexate-resistant Chinese hamster ovary cells.甲氨蝶呤耐药的中国仓鼠卵巢细胞中二氢叶酸还原酶的过量产生与基因扩增
Mol Cell Biol. 1982 Mar;2(3):275-85. doi: 10.1128/mcb.2.3.275-285.1982.
9
Transformation of mammalian cells with an amplifiable dominant-acting gene.用可扩增的显性作用基因转化哺乳动物细胞。
Proc Natl Acad Sci U S A. 1980 Jun;77(6):3567-70. doi: 10.1073/pnas.77.6.3567.
10
Increased dihydrofolate reductase activity in methotrexate-resistant human promyelocytic-leukaemia (HL-60) cells. Lack of correlation between increased activity and overproduction.甲氨蝶呤耐药的人早幼粒细胞白血病(HL-60)细胞中二氢叶酸还原酶活性增加。活性增加与过量产生之间缺乏相关性。
Biochem J. 1985 Feb 1;225(3):609-17. doi: 10.1042/bj2250609.