大鼠颅内自我刺激与苯丙胺自我给药同时进行。
Concurrent intracranial self-stimulation and amphetamine self-administration in rats.
作者信息
Wise R A, Yokel R A, Hansson P A, Gerber G J
出版信息
Pharmacol Biochem Behav. 1977 Nov;7(5):459-61. doi: 10.1016/0091-3057(77)90214-3.
PMID:563601
Abstract
In a two-lever testing chamber, rats had concurrent access to intravenous amphetamine and brain stimulation reinforcers. Responding for each reinforcer was generally increased above baseline rates taken when only one reinforcer was available. Amphetamine stereotypy was observed, but did not interfere with rapid lever-pressing for brain stimulation.
摘要
在一个双杠杆测试箱中，大鼠可以同时获得静脉注射苯丙胺和脑刺激强化物。与仅有一种强化物可用时所记录的基线速率相比，对每种强化物的反应通常有所增加。观察到了苯丙胺刻板行为，但这并未干扰为获得脑刺激而进行的快速杠杆按压。
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