Treton J A, Courtois Y, Lang J
Biomedicine. 1977 Nov;27(8):303-7.
Cultivated epithelial lens cells have been submitted to a 20 kHz continuous ultrasonic irradiation. At relativity high intensity, destruction of the cells was observed. At lower intensities, where no cell destruction appeared, the molecular weight of the single strand DNA of these cells was monitored to determine whether breakage of DNA molecules was induced by the ultrasound. No breakage of the single strand DNA was observed for intensities below 0.1 and 0.4 W cm-2 with irradiation times of less than 20 minutes and 15 seconds, respectively. These intensities and their corresponding irradiation time are higher than those used in current diagnostic practice.
培养的上皮晶状体细胞已接受20 kHz的连续超声照射。在相对较高的强度下，观察到细胞被破坏。在较低强度下，未出现细胞破坏，对这些细胞的单链DNA分子量进行监测，以确定超声是否会诱导DNA分子断裂。在强度分别低于0.1 W/cm²和0.4 W/cm²、照射时间分别少于20分钟和15秒时，未观察到单链DNA断裂。这些强度及其相应的照射时间高于当前诊断实践中使用的强度和时间。
