Mudraia I S, Nikolaev V G, Galinskaia V I, Aleĭnikov V G, Medvedev S L
Biull Eksp Biol Med. 1977 Dec;84(12):653-6.
The results of study of the sorption properties of phenolformaldehide-activated coal in respect of several physiologically active substances from the physiological saline under static conditoins and under conditions of autohemoperfusion of the limb vessels in experimental animals are presented. Phenolformaldehide-activated coal proved to sorb actively serotonin, adrenaline and noradrenaline, and--to a lesser extent--histamine from physiological saline. Serotonin, adrenaline, noradrenaline, and acetylcholine are sorbed well, histamine--less, papaverine--very weakly from the flowing blood. No alteration of the systemic arterial blood pressure was noted with the inclusion of phenolformaldehide-activated coal into the animal's arterial circulation; a fall of perfusion pressure associated with the decreased vascular resistance occured in a number of cases.
本文介绍了在静态条件下以及实验动物肢体血管自身血液灌注条件下，酚醛活化煤对生理盐水中几种生理活性物质的吸附特性研究结果。酚醛活化煤被证明能从生理盐水中积极吸附血清素、肾上腺素和去甲肾上腺素，对组胺的吸附程度较小。血清素、肾上腺素、去甲肾上腺素和乙酰胆碱能被很好地吸附，组胺吸附较少，罂粟碱从流动血液中的吸附非常微弱。将酚醛活化煤纳入动物动脉循环时，未观察到体循环动脉血压的改变；在一些情况下，出现了与血管阻力降低相关的灌注压下降。
