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动脉低氧血症:心脏手术后使用静脉注射异丙肾上腺素的一种副作用。

Arterial hypoxaemia: a side-effect of intravenous isoprenaline used after cardiac surgery.

作者信息

Fordham R M, Resnekov L

出版信息

Thorax. 1968 Jan;23(1):19-23. doi: 10.1136/thx.23.1.19.

Abstract

Intravenous administration of isoprenaline following cardiac surgery has been shown to cause an increase in existing arterial hypoxaemia. This is considered to be due to an increase in venous admixture following interference with the normal compensatory mechanism which in the presence of alveolar hypoxia tends to maintain normal ventilation-perfusion relationships.

摘要

心脏手术后静脉注射异丙肾上腺素已被证明会导致现有的动脉血氧不足加剧。这被认为是由于正常代偿机制受到干扰后静脉血掺杂增加所致,在存在肺泡缺氧的情况下,正常代偿机制往往会维持正常的通气-灌注关系。

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PULMONARY VENTILATION-PERFUSION RELATIONS AFTER HEART VALVE REPLACEMENT OF REPAIR IN MAN.
J Clin Invest. 1965 Mar;44(3):406-16. doi: 10.1172/JCI105154.
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Venous admixture in the pulmonary circulation of anestethetized dogs.
J Appl Physiol. 1960 May;15:418-24. doi: 10.1152/jappl.1960.15.3.418.
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