静脉注射异丙肾上腺素和沙丁胺醇对犬心肺功能的影响。
Cardiorespiratory effects of intravenous isoprenaline and salbutamol in dogs.
作者信息
Loh L, Seed R F, Sykes M K
出版信息
Br J Pharmacol. 1971 Mar;41(3):445-53. doi: 10.1111/j.1476-5381.1971.tb08042.x.
Abstract
- The cardiorespiratory effects of intravenous infusions of isoprenaline and salbutamol (1 and 5 mug/min) have been compared in twelve dogs.2. Both drugs produced a rise in pulse rate, a fall in systemic arterial pressure and a rise in pulmonary arterial pressure. Salbutamol produced a greater increase in cardiac output than isoprenaline.3. Both drugs produced an increase in venous admixture, but a significant fall in arterial oxygen tension occurred only with isoprenaline at the higher dose.
摘要
已对12只犬静脉输注异丙肾上腺素和沙丁胺醇（1和5微克/分钟）的心肺效应进行了比较。
两种药物均使心率升高、体动脉压下降及肺动脉压升高。沙丁胺醇使心输出量的增加幅度大于异丙肾上腺素。
两种药物均使静脉混合血增加，但仅高剂量异丙肾上腺素使动脉血氧张力显著下降。
相似文献
1
Cardiorespiratory effects of intravenous isoprenaline and salbutamol in dogs.静脉注射异丙肾上腺素和沙丁胺醇对犬心肺功能的影响。
Br J Pharmacol. 1971 Mar;41(3):445-53. doi: 10.1111/j.1476-5381.1971.tb08042.x.
2
The effect of intravenous isoprenaline, salbutamol and adrenaline on cardiorespiratory function in the dog.
Br J Anaesth. 1970 Jun;42(6):558.
3
The cardiorespiratory effects of intravenous isoprenaline in mechanically ventilated dogs.
Br J Anaesth. 1970 Dec;42(12):1042-50. doi: 10.1093/bja/42.12.1042.
4
Comparison of the bronchodilator and cardiovascular actions of salbutamol, isoprenaline and orciprenaline in guinea-pigs and dogs.沙丁胺醇、异丙肾上腺素和奥西那林对豚鼠和犬支气管扩张及心血管作用的比较
Br J Pharmacol. 1971 Nov;43(3):624-38. doi: 10.1111/j.1476-5381.1971.tb07192.x.
5
Comparison of cardiorespiratory effects of isoprenaline and salbutamol in patients with bronchial asthma.支气管哮喘患者中异丙肾上腺素与沙丁胺醇心肺效应的比较。
Br Med J. 1970 Jan 10;1(5688):65-70.
6
Comparison of effect of salbutamol and isoprenaline on spirometry and blood-gas tensions in bronchial asthma.沙丁胺醇与异丙肾上腺素对支气管哮喘患者肺量测定及血气张力影响的比较
Br Med J. 1970 Apr 4;2(5700):23-4. doi: 10.1136/bmj.2.5700.23.
7
Bronchodilating and cardiovascular effects of intraduodenally and orally administered clenbuterol in dogs.犬经十二指肠和口服给予克伦特罗后的支气管扩张及心血管效应
Arzneimittelforschung. 1985;35(7):1037-41.
8
Comparison of the effects of isoprenaline, orciprenaline, salbutamol and isoetharine on the cardiovascular system of anaesthetized dogs.异丙肾上腺素、奥西那林、沙丁胺醇和异他林对麻醉犬心血管系统作用的比较。
Br J Pharmacol. 1971 Sep;43(1):23-31. doi: 10.1111/j.1476-5381.1971.tb07153.x.
9
Cardiopulmonary effects of halothane in hypovolemic dogs.氟烷对低血容量犬的心肺影响。
Am J Vet Res. 1994 Jan;55(1):121-6.
10
Further observations on the cardiotoxicity of isoprenaline during hypoxia.关于缺氧时异丙肾上腺素心脏毒性的进一步观察
Br J Pharmacol. 1974 Mar;50(3):335-44. doi: 10.1111/j.1476-5381.1974.tb09608.x.
本文引用的文献
1
CONSTRUCTION AND USE OF SELF-GUIDING, RIGHT HEART AND PULMONARY ARTERY CATHETER.自引导式右心及肺动脉导管的构造与使用
J Appl Physiol. 1965 Jan;20:148-9. doi: 10.1152/jappl.1965.20.1.148.
2
ISOPROTERENOL AND CARDIOVASCULAR PERFORMANCE.异丙肾上腺素与心血管功能
Am J Med. 1964 Oct;37:514-25. doi: 10.1016/0002-9343(64)90065-8.
3
Cardiovascular effects of isoproterenol in normal subjects and subjects with congestive heart failure.异丙肾上腺素对正常受试者和充血性心力衰竭受试者的心血管影响。
Am Heart J. 1960 Jul;60:94-105. doi: 10.1016/0002-8703(60)90063-6.
4
The effect of acetylcholine on the human pulmonary circulation under normal and hypoxic conditions.乙酰胆碱在正常和低氧条件下对人体肺循环的影响。
J Clin Invest. 1958 Jan;37(1):99-110. doi: 10.1172/JCI103590.
5
Response of blood gas tensions to aminophylline and isoprenaline in patients with asthma.哮喘患者血气张力对氨茶碱和异丙肾上腺素的反应。
Thorax. 1967 Nov;22(6):543-9. doi: 10.1136/thx.22.6.543.
6
pH and blood-gas analysis. Methods of measurement and sources of error using electrode systems.
Anaesthesia. 1967 Oct;22(4):575-97. doi: 10.1111/j.1365-2044.1967.tb10156.x.
7
8
Effects of isoproterenol on the pulmonary circulation in obstructive airways disease.异丙肾上腺素对阻塞性气道疾病肺循环的影响。
Clin Sci. 1967 Apr;32(2):177-87.
9
Determination of the blood-gas factor of the oxygen electrode using a new tonometer.使用新型张力计测定氧电极的血气因子。
Br J Anaesth. 1967 Feb;39(2):107-13. doi: 10.1093/bja/39.2.107.
10
An effect of isoproterenol on ventilation-perfusion in asthmatic versus normal subjects.异丙肾上腺素对哮喘患者与正常受试者通气-灌注的影响。
J Appl Physiol. 1967 Mar;22(3):402-6. doi: 10.1152/jappl.1967.22.3.402.
Zotero 插件