血红蛋白 Bibba 或α-2-136Pro-β2，一种不稳定的α链异常血红蛋白。 - Suppr

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Hemoglobin-Bibba or alpha-2-136Pro-beta 2, an unstable alpha chain abnormal hemoglobin.

作者信息

Kleihauer E F, Reynolds C A, Dozy A M, Wilson J B, Moores R R, Berenson M P, Wright C S, Huisman T H

出版信息

Biochim Biophys Acta. 1968 Jan 22;154(1):220-2. doi: 10.1016/0005-2795(68)90274-2.

DOI:10.1016/0005-2795(68)90274-2

PMID:5639009

Abstract

摘要

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Hemoglobin-Bibba or alpha-2-136Pro-beta 2, an unstable alpha chain abnormal hemoglobin.血红蛋白 Bibba 或α-2-136Pro-β2，一种不稳定的α链异常血红蛋白。

Biochim Biophys Acta. 1968 Jan 22;154(1):220-2. doi: 10.1016/0005-2795(68)90274-2.

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Hb Bibba or alpha 2 136(H19)Leu-->Pro beta 2 in a Caucasian family from Alabama.

Hemoglobin. 1995 May-Jul;19(3-4):151-64. doi: 10.3109/03630269509036935.

Hb Mizuho [beta 68(E12)Leu----Pro]. Second occurrence identified in a Caucasian child with hemolytic anemia and dense erythrocyte inclusions.

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Unstable hemoglobin beta 32 (B 14) Leu leads to Pro, a new case discovered in Kobe.

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Human abnormal hemoglobins. 11. A chemical study of hemoglobin Lepore from a homozygote individual.人类异常血红蛋白。11. 对一名纯合子个体的血红蛋白Lepore的化学研究。

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Hb-Genova ( 2 2 28(B10)Leu leads to Pro ); methods for detection and analysis of unstable hemoglobins.血红蛋白热那亚（2 2 28（B10）位亮氨酸突变为脯氨酸）；不稳定血红蛋白的检测与分析方法

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引用本文的文献

alpha-Thalassemia caused by an unstable alpha-globin mutant.由不稳定的α-珠蛋白突变体引起的α-地中海贫血。

J Clin Invest. 1983 Mar;71(3):461-6. doi: 10.1172/jci110790.

Hereditary non-spherocytic haemolytic anaemia with post-splenectomy inclusion bodies and pigmenturia caused by an unstable haemoglobin Santa Ana-beta-88 (F4) leucine--proline.遗传性非球形细胞溶血性贫血，伴有脾切除术后包涵体和色素尿，由不稳定血红蛋白圣安娜-β-88（F4）亮氨酸-脯氨酸引起。

J Med Genet. 1968 Dec;5(4):292-7. doi: 10.1136/jmg.5.4.292.

Two new pathological haemoglobins: Olmsted beta 141 (H19) Leu leads to Arg and Malmö beta 97 (FG4) His leads to Gln.两种新的病理性血红蛋白：奥姆斯特德β141（H19）亮氨酸突变为精氨酸和马尔默β97（FG4）组氨酸突变为谷氨酰胺。

Biochem J. 1970 Oct;119(5):68P. doi: 10.1042/bj1190068pa.

The role of hemoglobin heme loss in Heinz body formation: studies with a partially heme-deficient hemoglobin and with genetically unstable hemoglobins.血红蛋白血红素丢失在亨氏小体形成中的作用：使用部分血红素缺乏的血红蛋白和遗传不稳定血红蛋白的研究

J Clin Invest. 1970 Nov;49(11):2008-16. doi: 10.1172/JCI106421.

[Hb frankfurt: a new unstable haemoglobin as the cause of Heinz-body anaemia in a German family].[血红蛋白法兰克福：一种新的不稳定血红蛋白，为德国家庭中亨氏小体贫血的病因]

Klin Wochenschr. 1971 Oct 15;49(20):1115-20. doi: 10.1007/BF01487586.

[Properties of the unstable Hb Wien].[不稳定血红蛋白维也纳的特性]

Klin Wochenschr. 1972 Oct 1;50(19):907-9. doi: 10.1007/BF01487920.

Hemoglobin Abraham Lincoln, beta32 (B14) leucine leads to proline. An unstable variant producing severe hemolytic disease.血红蛋白亚伯拉罕·林肯，β32（B14）位的亮氨酸突变为脯氨酸。一种导致严重溶血性疾病的不稳定变体。

J Clin Invest. 1973 Jul;52(7):1746-55. doi: 10.1172/JCI107356.

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