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The action of Ca2+ , Mg2+ and H+ on the contraction threshold of frog skeletal muscle: Evidence for surface charges controlling electro-mechanical coupling.钙离子、镁离子和氢离子对青蛙骨骼肌收缩阈值的作用：表面电荷控制机电耦合的证据。
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本文引用的文献

1
Delayed rectification and anomalous rectification in frog's skeletal muscle membrane.青蛙骨骼肌膜中的延迟整流和异常整流。
J Gen Physiol. 1962 Sep;46(1):97-115. doi: 10.1085/jgp.46.1.97.
2
THE EFFECT OF ZINC ON THE ELECTRICAL PROPERTIES OF MEMBRANE AND THE TWITCH TENSION IN FROG MUSCLE FIBRES.锌对蛙肌纤维膜电特性及单收缩张力的影响
Jpn J Physiol. 1964 Oct 15;14:538-50. doi: 10.2170/jjphysiol.14.538.
3
THE ACTION OF CALCIUM IONS ON POTASSIUM CONTRACTURES OF SINGLE MUSCLE FIBRES.钙离子对单根肌纤维钾挛缩的作用
J Physiol. 1963 Oct;168(3):679-97. doi: 10.1113/jphysiol.1963.sp007215.
4
Potassium contractures in single muscle fibres.单根肌纤维中的钾挛缩
J Physiol. 1960 Sep;153(2):386-403. doi: 10.1113/jphysiol.1960.sp006541.
5
Non-linear current-potential relations in an axon membrane.轴突膜中的非线性电流-电位关系。
J Gen Physiol. 1961 Jul;44(6):1055-7. doi: 10.1085/jgp.44.6.1055.
6
The control of membrane ionic currents by the membrane potential of muscle.肌肉膜电位对膜离子电流的控制。
J Gen Physiol. 1959 May 20;42(5):923-30. doi: 10.1085/jgp.42.5.923.
7
The action of calcium on the electrical properties of squid axons.钙对鱿鱼轴突电特性的作用。
J Physiol. 1957 Jul 11;137(2):218-44. doi: 10.1113/jphysiol.1957.sp005808.
8
The effect of tetraethylammonium chloride on the muscle membrane examined with an intracellular microelectrode.用细胞内微电极检测氯化四乙铵对肌膜的作用。
J Physiol. 1955 Sep 28;129(3):513-27. doi: 10.1113/jphysiol.1955.sp005374.
9
Voltage clamp experiments in skeletal muscle fibres.骨骼肌纤维中的电压钳实验。
J Physiol. 1966 Oct;186(2):51P-52P.

钙对青蛙骨骼肌收缩阈值和传导阈值的影响。

The effect o f calcium on contraction and conductance thresholds in frog skeletal muscle.

作者信息

Costantin L L

出版信息

J Physiol. 1968 Mar;195(1):119-32. doi: 10.1113/jphysiol.1968.sp008450.

DOI:10.1113/jphysiol.1968.sp008450
PMID:5639795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1557907/
Abstract
  1. The effect of extracellular calcium and magnesium on the contraction threshold and on the thresholds for an increase in sodium and potassium conductance with depolarization was studied in voltage-clamped frog muscle fibres.2. A larger depolarization was required to reach each of the three thresholds when the concentration of divalent cation was increased.3. The contraction and potassium conductance thresholds appeared to shift in parallel with alterations in calcium over the concentration range 0.2-10.0 mM and in magnesium over the concentration range 5.4-90.0 mM. The shift amounted to about 4 mV for a threefold change in concentration of divalent cation.4. The sodium conductance threshold was much more sensitive to alterations in divalent cation concentration than was either the contraction or the potassium conductance threshold.
摘要

  1. 在电压钳制的青蛙肌肉纤维中，研究了细胞外钙和镁对收缩阈值以及去极化时钠和钾电导增加阈值的影响。

  2. 当二价阳离子浓度增加时，达到三个阈值中的每一个都需要更大的去极化。

  3. 在0.2 - 10.0 mM的钙浓度范围和5.4 - 90.0 mM的镁浓度范围内，收缩和钾电导阈值似乎与钙和镁的变化平行移动。二价阳离子浓度三倍变化时，移动幅度约为4 mV。

  4. 钠电导阈值比收缩或钾电导阈值对二价阳离子浓度的变化更敏感。