钙对青蛙骨骼肌收缩阈值和传导阈值的影响。
The effect o f calcium on contraction and conductance thresholds in frog skeletal muscle.
作者信息
Costantin L L
出版信息
J Physiol. 1968 Mar;195(1):119-32. doi: 10.1113/jphysiol.1968.sp008450.
Abstract
- The effect of extracellular calcium and magnesium on the contraction threshold and on the thresholds for an increase in sodium and potassium conductance with depolarization was studied in voltage-clamped frog muscle fibres.2. A larger depolarization was required to reach each of the three thresholds when the concentration of divalent cation was increased.3. The contraction and potassium conductance thresholds appeared to shift in parallel with alterations in calcium over the concentration range 0.2-10.0 mM and in magnesium over the concentration range 5.4-90.0 mM. The shift amounted to about 4 mV for a threefold change in concentration of divalent cation.4. The sodium conductance threshold was much more sensitive to alterations in divalent cation concentration than was either the contraction or the potassium conductance threshold.
摘要
在电压钳制的青蛙肌肉纤维中，研究了细胞外钙和镁对收缩阈值以及去极化时钠和钾电导增加阈值的影响。
当二价阳离子浓度增加时，达到三个阈值中的每一个都需要更大的去极化。
在0.2 - 10.0 mM的钙浓度范围和5.4 - 90.0 mM的镁浓度范围内，收缩和钾电导阈值似乎与钙和镁的变化平行移动。二价阳离子浓度三倍变化时，移动幅度约为4 mV。
钠电导阈值比收缩或钾电导阈值对二价阳离子浓度的变化更敏感。
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