De Boeck S, Stockx J
Enzyme. 1978;23(1):56-63. doi: 10.1159/000458550.
All attempts to prove the presence of xanthine oxidase and uricase in yolk preparations failed. We were able instead to show that yolk preparations could hydrolyze the N1-C6 bond of certain purine bases. In the case of xanthine, 4-ureido-imidazole-5-carboxylic acid and 4-ureido-imidazole are formed. Activity only becomes apparent during purification. An analogous enzyme was described earlier in Clostridium cyclindrosporum. The liver and the blood plasma of actively laying hens do not contain the enzyme. A scheme for the degradation of egg ribonucleic acids is presented.
所有证明蛋黄制品中存在黄嘌呤氧化酶和尿酸酶的尝试均告失败。相反,我们能够证明蛋黄制品可以水解某些嘌呤碱的N1-C6键。就黄嘌呤而言,会形成4-脲基咪唑-5-羧酸和4-脲基咪唑。该活性仅在纯化过程中才会显现出来。之前在柱状芽孢梭菌中曾描述过一种类似的酶。正在产蛋的母鸡的肝脏和血浆中不含这种酶。本文还给出了鸡蛋核糖核酸的降解示意图。