Oda M, Nagashima K, Konishi Y
J Neurol. 1975 Dec 2;211(1):69-76. doi: 10.1007/BF00312465.
The brain of a 21-year-old man with imbecility and spastic tetraplegia since early childhood showed a diffuse sclerosis of the cerebral white matter and symmetrical degeneration of the thalamus and olivocerebellar system. The spinal nerve roots as well as proximal branches of the spinal nerves were hypertrophic and there was seen a marked fibrosis with some onion-bulb formations of Schwann cells. In spite of a possible relation to an unknown infection at the age of 3 months this case could preferably be regarded as a peculiar form of the combined system degeneration in the early childhood, including the cerebral white matter and peripheral nerves. An uncle of the patient had died of a similar nervous disease at the age of 20 years.
一名自幼年起就患有低能和痉挛性四肢瘫痪的21岁男性，其大脑显示出脑白质弥漫性硬化以及丘脑和橄榄小脑系统的对称性退化。脊神经根以及脊神经的近端分支肥大，可见明显的纤维化，伴有一些施万细胞的洋葱球样结构。尽管可能与3个月大时的一次未知感染有关，但该病例最好被视为儿童早期一种特殊形式的联合系统退化，包括脑白质和周围神经。患者的一位叔叔在20岁时死于类似的神经系统疾病。
