Morin L P, Fleming A S
J Comp Physiol Psychol. 1978 Feb;92(1):1-6. doi: 10.1037/h0077435.
Food intake and body weight of hamsters fluctuated systematically with the estrous cycle. Food intake and body weight were lowest when elevated endogenous estrogen levels were expected. Ovariectomized hamsters gained a significant amount of body weight compared with sham-operated animals. Replacement therapy with estradioal benzoate reduced the body weight and food intake of ovariectomized animals relative to oil-injected, ovariectomized control animals. The results are compared with similar data from rats and support the concept that in females of both species estradiol operates to regulate food intake and body weight.
仓鼠的食物摄入量和体重会随着发情周期而系统性波动。当预计内源性雌激素水平升高时，食物摄入量和体重最低。与假手术动物相比，卵巢切除的仓鼠体重显著增加。相对于注射油的卵巢切除对照动物，用苯甲酸雌二醇进行替代疗法可降低卵巢切除动物的体重和食物摄入量。将这些结果与来自大鼠的类似数据进行比较，支持了这样一种观点，即两种物种的雌性中，雌二醇都起着调节食物摄入量和体重的作用。
