葡萄球菌青霉素酶与6-[D(-)-α-胍基苯乙酰胺基]青霉烷酸的相互作用
Interaction of staphylococcal penicillinase and 6-[D(-)-alphaguanidino-phenylacetamido]-penicillanic acid.
作者信息
Thiele E H, Robinson H J
出版信息
Appl Microbiol. 1968 Feb;16(2):228-31. doi: 10.1128/am.16.2.228-231.1968.
Abstract
6[d(-)-alpha-Guanidinophenylacetamido]-penicillanic acid was shown to be significantly hydrolyzed by only one of six preparations of staphylococcal penicillinase. This penicillin analogue is a stronger penicillinase inactivator than are nafcillin and methicillin, which were not significantly hydrolyzed by the enzyme.
摘要
6[d(-)-α-胍基苯乙酰胺基]青霉烷酸仅在六种葡萄球菌青霉素酶制剂中的一种作用下被显著水解。这种青霉素类似物是比萘夫西林和甲氧西林更强的青霉素酶灭活剂，后两者未被该酶显著水解。
相似文献
1
Interaction of staphylococcal penicillinase and 6-[D(-)-alphaguanidino-phenylacetamido]-penicillanic acid.葡萄球菌青霉素酶与6-[D(-)-α-胍基苯乙酰胺基]青霉烷酸的相互作用
Appl Microbiol. 1968 Feb;16(2):228-31. doi: 10.1128/am.16.2.228-231.1968.
2
Clinical significance of protein binding of the penicillins.青霉素蛋白结合的临床意义。
Ann N Y Acad Sci. 1967 Sep 27;145(2):282-90. doi: 10.1111/j.1749-6632.1967.tb50225.x.
3
Some properties of two extracellular beta-lactamases from Bacillus cereus 569/H.蜡样芽孢杆菌569/H中两种细胞外β-内酰胺酶的一些特性
Biochem J. 1967 Jun;103(3):27C-30C. doi: 10.1042/bj1030027c.
4
Reliability of in vitro susceptibility tests for detecting coagulase-negative staphylococcal resistance to penicillinase-resistant semisynthetic penicillins.检测凝固酶阴性葡萄球菌对耐青霉素酶半合成青霉素耐药性的体外药敏试验的可靠性
J Clin Microbiol. 1983 Nov;18(5):1122-6. doi: 10.1128/jcm.18.5.1122-1126.1983.
5
[Clinical strains of staphylococci resistant to semisynthetic penicillins].[对半合成青霉素耐药的葡萄球菌临床菌株]
Antibiotiki. 1967 Oct;12(10):950-8.
6
Degradation of penicillin G and three semisynthetic penicillins by Bacillus cereus and Staphylococcus aureus penicillinase.蜡样芽孢杆菌和金黄色葡萄球菌青霉素酶对青霉素G及三种半合成青霉素的降解作用
Can J Microbiol. 1966 Feb;12(1):35-42. doi: 10.1139/m66-006.
7
Kinetics of beta-lactamase inactivation of penicillins. II. Effect of competitive inhibitors.青霉素β-内酰胺酶失活动力学。II. 竞争性抑制剂的作用
Chemotherapy. 1973;19(3):129-47. doi: 10.1159/000221449.
8
Substrate-specific inactivation of staphylococcal penicillinase.葡萄球菌青霉素酶的底物特异性失活
Biochem J. 1967 Jun;103(3):641-6. doi: 10.1042/bj1030641.
9
Reliability of high-content disks and modified broth dilution tests for detecting staphylococcal resistance to the penicillinase-resistant penicillins.用于检测葡萄球菌对耐青霉素酶青霉素耐药性的高含量平板和改良肉汤稀释试验的可靠性
J Clin Microbiol. 1987 Oct;25(10):1897-901. doi: 10.1128/jcm.25.10.1897-1901.1987.
10
The penicillins in ophthalmology.眼科中的青霉素。
Surv Ophthalmol. 1969 Jan;13(4):207-14.
本文引用的文献
1
Bacteriological studies on a new penicillin-BRL. 1241.关于新型青霉素BRL. 1241的细菌学研究。
Lancet. 1960 Sep 10;2(7150):564-7. doi: 10.1016/s0140-6736(60)91642-1.
2
AN EVALUATION OF CEPHALOSPORIN DERIVATIVES IN VITRO AND IN EXPERIMENTAL INFECTIONS.
J Pathol Bacteriol. 1964 Jul;88:125-36. doi: 10.1002/path.1700880116.
3
INHIBITION OF PENICILLINASES FROM GRAM-POSITIVE AND GRAM-NEGATIVE BACTERIA BY SUBSTRATE ANALOGUES.底物类似物对革兰氏阳性菌和革兰氏阴性菌青霉素酶的抑制作用
Nature. 1964 Mar 7;201:999-1001. doi: 10.1038/201999a0.
4
PURIFICATION AND PROPERTIES OF THE EXOPENICILLINASE FROM STAPHYLOCOCCUS AUREUS.金黄色葡萄球菌外青霉素酶的纯化及性质
Biochem J. 1963 Sep;88(3):452-9. doi: 10.1042/bj0880452.
5
STUDIES ON PENICILLINASE PRODUCED BY A STRAIN OF STAPHYLOCOCCUS AUREUS.一株金黄色葡萄球菌产生的青霉素酶的研究。
Proc R Soc Lond B Biol Sci. 1963 Oct 22;158:311-28. doi: 10.1098/rspb.1963.0050.
6
The nature of resistance of a penicillin to hydrolysis by pencillinase.
J Pharm Pharmacol. 1962 Dec;14:784-93. doi: 10.1111/j.2042-7158.1962.tb11177.x.
7
Inactivation of staphylococcal penicillinase by reaction with resistant penicillins.通过与耐酶青霉素反应使葡萄球菌青霉素酶失活。
Nature. 1962 Aug 4;195:496-7. doi: 10.1038/195496a0.
8
Behaviour of some derivatives of 7-aminocephalosporanic acid and 6-aminopenicillanic acidas substrates, inhibitors and inducers of penicillinases.7-氨基头孢烷酸和6-氨基青霉烷酸的某些衍生物作为青霉素酶底物、抑制剂和诱导剂的行为。
Biochem J. 1962 Apr;83(1):52-63. doi: 10.1042/bj0830052.
9
Pencillin resistance compared to penicillinase production in cultures of Staphylococcus aureus grown anaerobically and aerobically.在需氧和厌氧培养的金黄色葡萄球菌培养物中，青霉素耐药性与青霉素酶产生情况的比较。
Antibiot Chemother (Northfield). 1960 Jan;10:20-4.
10
Staphylococcal penicillinase. I. Inhibition and stimulation of activity.葡萄球菌青霉素酶。I. 活性的抑制与刺激
J Bacteriol. 1961 Aug;82(2):298-304. doi: 10.1128/jb.82.2.298-304.1961.
Zotero 插件