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脂质双层中的抗性变化:免疫学应用。

Resistance changes in lipid bilayers: immunological applications.

作者信息

Barfort P, Arquilla E R, Vogelhut P O

出版信息

Science. 1968 Jun 7;160(3832):1119-21. doi: 10.1126/science.160.3832.1119.

DOI:10.1126/science.160.3832.1119
PMID:5647433
Abstract

The electrical resistance of a bimolecular lipid membrane in 0.1 molar NaCl decreases if antibody and complement are present on one side of the membrane and the homologous antigen is added to the other side. The reaction occurs within minutes and requires less than 0.1 microliter of antiserum.

摘要

在0.1摩尔氯化钠溶液中,如果双分子脂质膜一侧存在抗体和补体,而另一侧加入同源抗原,那么该双分子脂质膜的电阻会降低。此反应在数分钟内发生,所需抗血清不到0.1微升。

相似文献

1
Resistance changes in lipid bilayers: immunological applications.脂质双层中的抗性变化:免疫学应用。
Science. 1968 Jun 7;160(3832):1119-21. doi: 10.1126/science.160.3832.1119.
2
Antibody binding and complement fixation by a liposomal model membrane.脂质体模型膜的抗体结合与补体固定
Biochemistry. 1969 Apr;8(4):1582-7. doi: 10.1021/bi00832a038.
3
[The interaction of antibody and complement with model membranes (author's transl)].抗体与补体和模型膜的相互作用(作者译)
Tanpakushitsu Kakusan Koso. 1974 Sep 17;19(10):741-54.
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Comparative responses of liposomes prepared with different ceramide antigens to antibody and complement.
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STUDIES ON LYSOLECITHIN FORMATION IN IMMUNE HEMOLYSIS.免疫溶血中溶血卵磷脂形成的研究。
J Immunol. 1965 Jan;94:40-6.
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Lesions due to complement in lipid membranes.脂质膜中补体引起的损伤。
Nature. 1971 Oct 29;233(5322):620-3. doi: 10.1038/233620a0.
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Preparation of immunologically responsive liposomes with phosphonyl and phosphinyl analogs of lecithin.用卵磷脂的膦酰基和次膦酰基类似物制备免疫反应性脂质体。
Biochim Biophys Acta. 1971 Jun 1;233(3):815-9. doi: 10.1016/0005-2736(71)90183-0.
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Immune lysis of reconstituted myelin basic protein--lipid vesicles and myelin vesicles.
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Complement-dependent damage to liposomes prepared from pure lipids and Forssman hapten.补体依赖的对由纯脂质和福斯曼半抗原制备的脂质体的损伤。
Biochemistry. 1969 Oct;8(10):4149-58. doi: 10.1021/bi00838a036.
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引用本文的文献

1
Lipid-polypeptide interactions in bilayer lipid membranes.双层脂质膜中的脂质-多肽相互作用。
J Membr Biol. 1972 Dec;7(1):245-66. doi: 10.1007/BF01867918.
2
Properties of lipid bilayer membranes separating two aqueous phases: The effects of Fe(+3) on electrical properties.双层脂膜分隔两个水相的性质:Fe(+3)对电性质的影响。
J Membr Biol. 1972 Dec;7(1):54-87. doi: 10.1007/BF01867909.
3
Hydrophobic interaction between the monomer of mitochondrial malate dehydrogenase and phospholipid membranes.线粒体苹果酸脱氢酶单体与磷脂膜之间的疏水相互作用。
Biochem J. 1980 Jan 15;186(1):227-33. doi: 10.1042/bj1860227.
4
Single channel currents induced by complement in antibody-coated cell membranes.补体在抗体包被的细胞膜上诱导产生的单通道电流。
Proc Natl Acad Sci U S A. 1981 Oct;78(10):6421-5. doi: 10.1073/pnas.78.10.6421.
5
Immune response of a liposomal model membrane.脂质体模型膜的免疫反应。
Proc Natl Acad Sci U S A. 1968 Sep;61(1):300-7. doi: 10.1073/pnas.61.1.300.
6
Electrical response to vibration of a lipid bilayer membrane.脂质双分子层膜对振动的电响应。
Biophys J. 1974 Jun;14(6):473-89. doi: 10.1016/S0006-3495(74)85928-X.
7
The effect of insulin on the permeability of phosphatidyl choline bimolecular membranes to glucose.胰岛素对磷脂酰胆碱双分子膜葡萄糖通透性的影响。
J Membr Biol. 1974;18(1):81-94. doi: 10.1007/BF01870104.
8
Pore formation by complement in the outer membrane of gram-negative bacteria studied with asymmetric planar lipopolysaccharide/phospholipid bilayers.利用不对称平面脂多糖/磷脂双层研究革兰氏阴性菌外膜中补体形成的孔道。
J Membr Biol. 1990 Nov;118(2):161-70. doi: 10.1007/BF01868473.
9
Increased ion permeability of planar lipid bilayer membranes after treatment with the C5b-9 cytolytic attack mechanism of complement.在用补体的C5b-9溶细胞攻击机制处理后,平面脂质双分子层膜的离子通透性增加。
Proc Natl Acad Sci U S A. 1976 Aug;73(8):2852-6. doi: 10.1073/pnas.73.8.2852.
10
Interaction of lymphocytes with lipid bilayer membranes: a model for lymphocyte-mediated lysis of target cells.淋巴细胞与脂质双层膜的相互作用:淋巴细胞介导的靶细胞裂解模型。
Proc Natl Acad Sci U S A. 1975 Jul;72(7):2789-93. doi: 10.1073/pnas.72.7.2789.