发情周期中松果体的脱氢酶活性。

Dehydrogenase activity of the pineal gland during the estrous cycle.

作者信息

Fasano A V, Kasprow B A, Velardo J T

出版信息

Endocr Res Commun. 1977;4(5):257-66. doi: 10.3109/07435807709052945.

Abstract

An investigation of the relationship of succinic dehydrogenase (SDH) and lactate dehydrogenase (LDH) in the pineal gland of the adult female albino rats was carried out during seven definitive stages of the estrous cycle: Early Estrus (E1), Late Estrus (E2), Metestrus (ME), Early Diestrus (D1), Late Diestrus (D2), Preproestrus (PPE) and Proestrus (PE). Controlled housing conditions were maintained on 7:00 A.M. to 7:00 P.M. light-dark cycle. The animals were necropsied at precise times after the onset of estrus and subsequent stages of the cycle. Comparative histochemical and biochemical analysis revealed the following for SDH activity: E2 greater than E1 greater than D2 greater than D1 greater than PPE greater than PE greater than ME; and for LDH activity: PE greater than E2 greater than ME greater than D1 greater than PPE greater than E1 greater than D2. Interrelationships are postulated between pineal SDH, GOT, GPT, and estrogen concentrations in the rat.

摘要

在成年雌性白化大鼠发情周期的七个确定阶段

动情前期（E1）、动情后期（E2）、间情期（ME）、动情间期早期（D1）、动情间期后期（D2）、发情前期（PPE）和发情期（PE），对松果体中琥珀酸脱氢酶（SDH）和乳酸脱氢酶（LDH）的关系进行了研究。在上午7:00至下午7:00的明暗循环条件下维持对照饲养条件。在发情开始及随后的周期阶段后的精确时间对动物进行尸检。比较组织化学和生化分析显示，SDH活性如下：E2＞E1＞D2＞D1＞PPE＞PE＞ME；LDH活性如下：PE＞E2＞ME＞D1＞PPE＞E1＞D2。推测大鼠松果体SDH、谷草转氨酶（GOT）、谷丙转氨酶（GPT）和雌激素浓度之间存在相互关系。