Drickamer L C, Murphy R X
Dev Psychobiol. 1978 Jan;11(1):63-72. doi: 10.1002/dev.420110110.
A sequence of 4 experiments examined the effects of prepubertal and adult males on the sexual maturation of young female house mice. The results support 3 conclusions: (1) the presence of a prepubertal male or of urine from prepubertal males does not affect the timing of sexual maturation in young female house mice; (2) the maturation-accelerating pheromone produced by adult males is present in the bladder urine of intact adult males but is absent from both excreted and bladder urine of castrated males; and (3) young females caged with 7 prepubertal males or with a castrated adult male mature earlier than control females caged alone. Results indicating that the presence of a castrated male leads to earlier sexual maturation of young female mice differ from previous findings. A possible explanation for this contradictory result is based on the ability of young weanling female mice to acclimatize the thermoregulate when separated from the dam and litter-mates. A model for density-feedback population regulation in house mice involving pheromones produced by males and females is presented.
一系列4个实验研究了青春期前雄性和成年雄性对年轻雌性家鼠性成熟的影响。结果支持3个结论：（1）青春期前雄性的存在或青春期前雄性的尿液不会影响年轻雌性家鼠性成熟的时间；（2）成年雄性产生的加速成熟信息素存在于完整成年雄性的膀胱尿液中，但阉割雄性的排泄尿液和膀胱尿液中均不存在；（3）与7只青春期前雄性或1只阉割成年雄性关在笼中的年轻雌性比单独关在笼中的对照雌性成熟更早。表明阉割雄性的存在会导致年轻雌性小鼠性成熟提前的结果与之前的研究结果不同。对这一矛盾结果的一种可能解释是基于年轻断奶雌性小鼠在与母鼠和同窝幼崽分离时适应温度调节的能力。提出了一个涉及雄性和雌性产生的信息素的家鼠密度反馈种群调节模型。
