Mammalian Reproduction Group, Institute of Zoology, Jagiellonian University, 30-060, Cracow, Poland.
J Chem Ecol. 1990 Oct;16(10):2817-22. doi: 10.1007/BF00979475.
Male mice produce pheromones that induce estrus in adult female mice. The synthesis of these chemosignals is controlled by testosterone. Male tissues abundant in testosterone-binding receptors were tested for their ability to stimulate estrus in grouped females. The percentage of females that showed estrus during two days following exposure to male tissues was used as the indicator of biological activity of tested samples. Homogenates of salivary glands and preputial glands induced estrus; other tested organs (liver, testes, coagulation and vesicular glands or kidneys) did not stimulate estrus in female mice. These results indicate that estrus-stimulating pheromone has multiple sources.
雄性老鼠会产生信息素，从而诱导成年雌性老鼠发情。这些化学信号的合成受睾酮控制。研究人员测试了富含睾酮结合受体的雄性组织，以检测其刺激成群雌性发情的能力。暴露于雄性组织后两天内发情的雌性比例被用作测试样本生物活性的指标。唾液腺和包皮腺的匀浆可诱导发情；其他测试的器官（肝脏、睾丸、凝血和囊状腺或肾脏）不能刺激雌性老鼠发情。这些结果表明，发情刺激信息素具有多种来源。
