Magos L
Br J Ind Med. 1968 Apr;25(2):152-4. doi: 10.1136/oem.25.2.152.
2,3-Dimercaptopropanol (BAL) given to rats in doses used for the treatment of acute mercury chloride poisoning in man increases the excretion of mercury. The mercury content of the brain was unaffected by 2,3-dimercaptopropanol unless it was given a short time after the mercuric chloride, when there was a 24% increase. The relevance of these findings to therapy with BAL is discussed.
给大鼠注射用于治疗人类急性氯化汞中毒的剂量的2,3-二巯基丙醇(BAL),会增加汞的排泄。除非在氯化汞给药后短时间内给予2,3-二巯基丙醇,否则大脑中的汞含量不受其影响,而在这种情况下大脑汞含量会增加24%。本文讨论了这些发现与BAL治疗的相关性。