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1
Effect of 2,3-dimercaptopropanol (BAL) on urinary excretion and brain content of mercury.2,3-二巯基丙醇(BAL)对汞尿排泄及脑汞含量的影响。
Br J Ind Med. 1968 Apr;25(2):152-4. doi: 10.1136/oem.25.2.152.
2
The excretion and distribution of inorganic mercury in the rat as influenced by several chelating agents.几种螯合剂对大鼠体内无机汞排泄和分布的影响。
Arch Toxicol. 1976 Jan 30;35(1):15-24. doi: 10.1007/BF00333982.
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Accelerated uptake of mercury by brain caused by 2,3-dimercaptopropanol (BAL) after injection into the mouse of a methylmercuric compound.将甲基汞化合物注射到小鼠体内后,2,3-二巯基丙醇(BAL)导致大脑对汞的摄取加速。
Acta Pharmacol Toxicol (Copenh). 1965;23(4):312-20. doi: 10.1111/j.1600-0773.1965.tb00356.x.
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The effect of immediate and delayed treatment with 2,3-dimercaptopropane-1-sulphonate on the distribution and toxicity of inorganic mercury in mice and in foetal and adult rats.2,3-二巯基丙烷-1-磺酸盐即时和延迟治疗对小鼠以及胎儿和成年大鼠体内无机汞分布和毒性的影响。
Acta Pharmacol Toxicol (Copenh). 1980 Feb;46(2):81-8. doi: 10.1111/j.1600-0773.1980.tb02425.x.
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[Effects of 2-3-dimercaptopropanol (BAL) on experimental subacute mercury poisoning; action mechanism].
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[Comparative study of the mercury content in the air during the use of mercury seed disinfectants and in the urine of exposed workers].
Z Arztl Fortbild (Jena). 1976 May 15;70(10):530-2.
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Comparison of the effectiveness of 2,3-dimercaptopropanol (BAL) and meso-2,3-dimercaptosuccinic acid (DMSA) as protective agents against mercuric chloride-induced nephrotoxicity in rats.2,3-二巯基丙醇(BAL)和内消旋-2,3-二巯基丁二酸(DMSA)作为大鼠氯化汞诱导肾毒性保护剂的效果比较
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[Dislocation and excretion of mercury in rats following application of unithiol].
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引用本文的文献

1
Psychiatric aspects of methylmercury poisoning.甲基汞中毒的精神科问题。
J Neurol Neurosurg Psychiatry. 1974 Aug;37(8):954-8. doi: 10.1136/jnnp.37.8.954.
2
Evaluation of the chelating action of methicillin in prolonged experimental metallic mercury poisoning.
Br J Ind Med. 1986 Sep;43(9):611-4. doi: 10.1136/oem.43.9.611.

本文引用的文献

1
CLINICAL USES OF 2,3-DIMERCAPTOPROPANOL (BAL). XI. THE TREATMENT OF ACUTE MERCURY POISONING BY BAL.二巯丙醇(BAL)的临床应用。十一、二巯丙醇治疗急性汞中毒
J Clin Invest. 1946 Jul;25(4):557-67. doi: 10.1172/JCI101738.

2,3-二巯基丙醇(BAL)对汞尿排泄及脑汞含量的影响。

Effect of 2,3-dimercaptopropanol (BAL) on urinary excretion and brain content of mercury.

作者信息

Magos L

出版信息

Br J Ind Med. 1968 Apr;25(2):152-4. doi: 10.1136/oem.25.2.152.

DOI:10.1136/oem.25.2.152
PMID:5647978
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1008728/
Abstract

2,3-Dimercaptopropanol (BAL) given to rats in doses used for the treatment of acute mercury chloride poisoning in man increases the excretion of mercury. The mercury content of the brain was unaffected by 2,3-dimercaptopropanol unless it was given a short time after the mercuric chloride, when there was a 24% increase. The relevance of these findings to therapy with BAL is discussed.

摘要

给大鼠注射用于治疗人类急性氯化汞中毒的剂量的2,3-二巯基丙醇(BAL),会增加汞的排泄。除非在氯化汞给药后短时间内给予2,3-二巯基丙醇,否则大脑中的汞含量不受其影响,而在这种情况下大脑汞含量会增加24%。本文讨论了这些发现与BAL治疗的相关性。