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甲基汞中毒的精神科问题。

Psychiatric aspects of methylmercury poisoning.

作者信息

Maghazaji H I

出版信息

J Neurol Neurosurg Psychiatry. 1974 Aug;37(8):954-8. doi: 10.1136/jnnp.37.8.954.

DOI:10.1136/jnnp.37.8.954
PMID:4420813
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC494811/
Abstract

Forty-three patients with methylmercury poisoning were studied; 74·4% showed some degree of depression. Their blood levels of mercury were higher than the average values for the whole group, and considerably higher than the blood levels of the non-depressed patients. Irritability was observed in 44·2% of the patients, all except one of the 19 being under 30 years of age. There was general improvement in the mental states of the patients who were hospitalized. Mercury binding compounds did not seem to have a significant effect in enhancing recovery from the depressive state. The possibility of there being two distinct syndromes, due to organic and inorganic mercury poisoning, is discussed.

摘要

对43名甲基汞中毒患者进行了研究;74.4%的患者表现出一定程度的抑郁。他们的血液汞含量高于整个组的平均值,且远高于未患抑郁症患者的血液汞含量。44.2%的患者表现出易怒,19名患者中除1名外,其他患者年龄均在30岁以下。住院患者的精神状态总体有所改善。汞结合化合物似乎对促进抑郁状态的恢复没有显著作用。文中讨论了因有机汞和无机汞中毒而出现两种不同综合征的可能性。

相似文献

1
Psychiatric aspects of methylmercury poisoning.甲基汞中毒的精神科问题。
J Neurol Neurosurg Psychiatry. 1974 Aug;37(8):954-8. doi: 10.1136/jnnp.37.8.954.
2
[Psychiatric aspects of Minamata disease (author's transl)].水俣病的精神科问题(作者译)
Seishin Shinkeigaku Zasshi. 1977 Aug 25;79(8):393-413.
3
Tissue levels of mercury in autopsy specimens of liver and kidney.肝脏和肾脏尸检标本中的汞组织水平。
Bull World Health Organ. 1976;53 Suppl(Suppl):93-7.
4
An outbreak of organomercury poisoning among Iraqi farmers.伊拉克农民群体中发生的有机汞中毒事件。
Bull World Health Organ. 1976;53 Suppl(Suppl):15-21.
5
Epidemiology of organomercury poisoning in Iraq. II. Relationship of mercury levels in blood and hair to exposure and to clinical findings.伊拉克有机汞中毒的流行病学。II. 血液和头发中的汞含量与暴露及临床发现的关系。
Bull World Health Organ. 1976;53 Suppl(Suppl):37-48.
6
Methyl mercury poisoning in Iraq. A neurological study.
Brain. 1974 Sep;97(3):500-10.
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[Toxic mental disorders].
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From the Centers for Disease Control and Prevention. Blood and hair mercury levels in young children and women of childbearing age--United States, 1999.来自美国疾病控制与预防中心。1999年美国幼儿及育龄妇女的血液和头发汞含量。
JAMA. 2001 Mar 21;285(11):1436-7.
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Mercury poisoning: a case of a complex neuropsychiatric illness.汞中毒:一例复杂的神经精神疾病病例。
Am J Psychiatry. 2014 Dec 1;171(12):1253-6. doi: 10.1176/appi.ajp.2013.12101266.
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Exchange transfusion treatment of methylmercury-poisoned children.甲基汞中毒儿童的换血治疗
J Environ Sci Health C. 1978;13(1):63-80.

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本文引用的文献

1
Poisoning by ethyl mercury toluene sulphonanilide.乙基汞甲苯磺酰苯胺中毒
Br J Ind Med. 1961 Oct;18(4):303-8. doi: 10.1136/oem.18.4.303.
2
THE HAZARD OF MERCURY POISONING: DON'T BE A MAD HATTER.汞中毒的危害:别成了疯帽匠。
J Am Coll Health Assoc. 1965 Apr;13:551-8.
3
Minamata disease. The outbreak of a neurologic disorder in Minamata, Japan, and its relationship to the ingestion of seafood contaminated by mercuric compounds.水俣病。日本水俣市一种神经系统疾病的爆发及其与摄入受汞化合物污染的海鲜的关系。
World Neurol. 1960 Nov;1:370-95.
4
Studies on the metabolism of mercuric chloride and methyl mercury dicyandiamide; experiments on rats given subcutaneous injections with radioactive mercury (Hg203).氯化汞和甲基汞双氰胺的代谢研究;给大鼠皮下注射放射性汞(Hg203)的实验。
AMA Arch Ind Health. 1959 Jul;20(1):42-9.
5
Effect of 2,3-dimercaptopropanol (BAL) on urinary excretion and brain content of mercury.2,3-二巯基丙醇(BAL)对汞尿排泄及脑汞含量的影响。
Br J Ind Med. 1968 Apr;25(2):152-4. doi: 10.1136/oem.25.2.152.
6
Alkylmercury contamination of foods.食品中的烷基汞污染。
JAMA. 1971 Jan 11;215(2):287-8.
7
Organic-mercury food poisoning.
N Engl J Med. 1971 Apr 1;284(13):706-9. doi: 10.1056/NEJM197104012841306.
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Methylmercury poisoning in Iraq.伊拉克的甲基汞中毒事件。
Science. 1973 Jul 20;181(4096):230-41. doi: 10.1126/science.181.4096.230.
9
Biochemical changes in the brain in rats poisoned with an alkymercury compound, with special reference to the inhibition of protein synthesis in brain cortex slices.用烷基汞化合物中毒的大鼠大脑中的生化变化,特别提及大脑皮层切片中蛋白质合成的抑制。
J Neurochem. 1966 Nov;13(11):1223-30. doi: 10.1111/j.1471-4159.1966.tb04281.x.