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“胰腺性糖尿病”中血清胰岛素对葡萄糖的反应

Serum-insulin response to glucose in "pancreatic diabetes".

作者信息

Bank S, Jackson W P, Keller P, Marks I N

出版信息

Postgrad Med J. 1968 Mar;44(509):214-7. doi: 10.1136/pgmj.44.509.214.

DOI:10.1136/pgmj.44.509.214
PMID:5648665
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2466360/
Abstract

Thirty patients with chronic pancreatitis (mostly calcific) were tested for glucose tolerance and serum insulin response to glucose loading. The responses were very variable and the insulin values did not clearly relate to the ‘glucose-tolerance-status’. Some subjects had low insulin levels throughout, some had average to high fasting levels without further response, and some showed an excellent rise of insulin level after glucose. No antibodies to insulin could be found in seven patients. Synalbumin antagonist was present at 1·25% in five out of twelve patients tested.

摘要

对30例慢性胰腺炎患者(大多为钙化性)进行了葡萄糖耐量和血清胰岛素对葡萄糖负荷反应的测试。反应差异很大,胰岛素值与“糖耐量状态”没有明显关联。一些受试者胰岛素水平始终较低,一些受试者空腹水平中等至较高但无进一步反应,还有一些受试者葡萄糖后胰岛素水平显著升高。7例患者未发现胰岛素抗体。在12例接受测试的患者中,有5例(1.25%)存在胰岛素白蛋白拮抗剂。

相似文献

1
Serum-insulin response to glucose in "pancreatic diabetes".“胰腺性糖尿病”中血清胰岛素对葡萄糖的反应
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2
[New method of glucose tolerance gauging: testing the differences in the plasma and erythrocyte glucose levels after loading with 59 g. of glucose].葡萄糖耐量测定的新方法:检测摄入59克葡萄糖后血浆和红细胞葡萄糖水平的差异
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The insulin response to glucose in patients with pancreatic disease.胰腺疾病患者对葡萄糖的胰岛素反应。
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[SUICIDE BY INSULIN].
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引用本文的文献

1
The insulin response to glucose in patients with pancreatic disease.胰腺疾病患者对葡萄糖的胰岛素反应。
Postgrad Med J. 1969 Nov;45(529):726-8. doi: 10.1136/pgmj.45.529.726.
2
Glucose tolerance, free fatty acid, and serum insulin responses in patients with cirrhosis.
Am J Dig Dis. 1969 Oct;14(10):691-9. doi: 10.1007/BF02233575.
3
Growth hormone responses to arginine infusion in patients with chronic pancreatitis: relationship to glucose intolerance and insulinopenia.慢性胰腺炎患者对精氨酸输注的生长激素反应:与葡萄糖耐量异常和胰岛素缺乏的关系。
Diabetologia. 1974 Oct;10(5):465-8. doi: 10.1007/BF01221639.
4
Gastric inhibitory polypeptide (GIP), gastrin and insulin: response to test meal in coeliac disease and after duodeno-pancreatectomy.胃抑肽(GIP)、胃泌素与胰岛素:乳糜泻患者及十二指肠-胰腺切除术后对试餐的反应
Diabetologia. 1976 Jul;12(3):279-86. doi: 10.1007/BF00422096.
5
Insulin secretion and pancreatic exocrine function in patients with chronic pancreatitis.慢性胰腺炎患者的胰岛素分泌与胰腺外分泌功能
Diabetologia. 1979 Jun;16(6):355-8. doi: 10.1007/BF01223154.
6
The endocrine pancreas in chronic pancreatitis. Immunocytochemical and ultrastructural studies.慢性胰腺炎中的内分泌胰腺。免疫细胞化学和超微结构研究。
Virchows Arch A Pathol Anat Histol. 1978 Feb 10;377(2):157-74. doi: 10.1007/BF00427003.

本文引用的文献

1
TREATMENT OF PANCREATIC DIABETES.胰腺性糖尿病的治疗
Mod Treat. 1965 May;2:471-6.
2
THE PANCREATIC-FUNCTION TEST--METHOD AND NORMAL VALUES.胰腺功能测试——方法及正常值
S Afr Med J. 1963 Oct 19;37:1061-6.
3
Immunologic aspects of insulin.胰岛素的免疫学方面
Am J Med. 1961 Dec;31:882-91. doi: 10.1016/0002-9343(61)90030-4.
4
Immunoassay of insulin with insulin-antibody precipitate.用胰岛素 - 抗体沉淀物进行胰岛素免疫测定。
Biochem J. 1963 Jul;88(1):137-46. doi: 10.1042/bj0880137.
5
The management of diabetes in the underprivileged, with special reference to pancreatic diabetes.弱势群体中糖尿病的管理,特别是胰腺性糖尿病
S Afr Med J. 1966 Apr 23;40(15):342-6.
6
Plasma-insulin levels in "pancreatic diabetes".“胰腺性糖尿病”中的血浆胰岛素水平。
Lancet. 1965 Dec 11;2(7424):1211-3. doi: 10.1016/s0140-6736(65)90635-5.