Woods K L, Heath D A
Clin Chim Acta. 1978 Mar 1;84(1-2):207-11. doi: 10.1016/0009-8981(78)90496-5.
Using a radioimmunoassay for the milk protein lactalbumin in human serum, we have found that falsely high results can be caused by cross-reacting human antibodies to bovine lactalbumin. A reliable method of circumventing this problem is described. When such interference had been eliminated, circulating lactalbumin was not detected in normal men or post-menopausal women, but could still be found in a proportion of non-pregnant, non-lactating pre-menopausal women.
通过用人血清中乳蛋白乳白蛋白的放射免疫测定法，我们发现人抗牛乳白蛋白的交叉反应性抗体可能导致结果出现假性升高。本文描述了一种规避此问题的可靠方法。当消除这种干扰后，在正常男性或绝经后女性中未检测到循环乳白蛋白，但仍能在一定比例的非妊娠、非哺乳的绝经前女性中发现。
