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菲律宾毛细线虫的进一步研究:该寄生虫在长爪沙鼠体内的发育

Further studies on Capillaria philippinensis: development of the parasite in the Mongolian gerbil.

作者信息

Cross J H, Banzon T, Singson C

出版信息

J Parasitol. 1978 Apr;64(2):208-13.

PMID:565396
Abstract

Capillaria philippinensis larvae from the digestive tract of a Northern Luzon freshwater fish (Hypselotris bipartita) experimentally exposed to embryonated eggs, were given by stomach tube to Mongolian gerbils (Meriones unguiculatus). The larvae developed into adults within 10 to 11 days and female worms produced larvae within 13 to 14 days. These larvae developed into second generation adults by days 22 to 24 and the second generation females produced eggs that were present in the feces of the animal on the average 26 days after infection. Most females were oviparous but a few larviparous females were always present. The gerbils died on an average of 46 days after infection, with the highest numbers of worms recovered between days 36 and 46. All stages of the parasite were generally found at necropsy. Gerbils developed patent infections after receiving 2 or 3 laeval from fish, and 852 to 5,353 worms were recovered at necropsy. These studies show that autoinfection in an integral part of the life cycle of C. philippinensis, both initially and in maintaining the infection. The natural transmission of the parasite was demonstrated when H. bipartita from a lagoon in the endemic area were fed to gerbils and 3 became infected. The parasite can also be maintained in the laboratory by transfer of worms by stomach tube from the small intestines of an infected gerbil to a clean gerbil.

摘要

从北吕宋淡水鱼(双线异齿脂鲤)消化道中获取的菲律宾毛细线虫幼虫,经实验暴露于感染性虫卵后,通过胃管投喂给蒙古沙鼠(长爪沙鼠)。幼虫在10至11天内发育为成虫,雌虫在13至14天内产出幼虫。这些幼虫在22至24天发育为第二代成虫,第二代雌虫产出的虫卵平均在感染后26天出现在动物粪便中。大多数雌虫为卵生,但总有少数胎生雌虫。沙鼠平均在感染后46天死亡,在36至46天之间回收的虫体数量最多。在尸检时通常能发现寄生虫的各个阶段。沙鼠在接受来自鱼的2或3条幼虫后出现显性感染,尸检时回收852至5353条虫体。这些研究表明,自身感染是菲律宾毛细线虫生命周期中不可或缺的一部分,无论是在初始阶段还是在维持感染方面。当将来自流行地区一个泻湖的双线异齿脂鲤投喂给沙鼠,有3只被感染时,证明了该寄生虫的自然传播。该寄生虫也可在实验室中通过胃管将虫体从感染沙鼠的小肠转移到清洁沙鼠体内来维持。

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Further studies on Capillaria philippinensis: development of the parasite in the Mongolian gerbil.菲律宾毛细线虫的进一步研究:该寄生虫在长爪沙鼠体内的发育
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