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气压病:由溶解气体引起的渗透作用?

Dysbarism: osmosis caused by dissolved gas?

作者信息

Kylstra J A, Longmuir I S, Grace M

出版信息

Science. 1968 Jul 19;161(3838):289. doi: 10.1126/science.161.3838.289.

Abstract

The pressure in an osmometer, filled with nitrous oxide-saturated water separated from water by a polyurethane polyether membrane 2.5 microns in thickness, rose slowly by 8 to 20 millimeters (of water) in 10 minutes before gradually returning to close to zero within 2 hours. The permeation coefficient of the membrane was approximately 1000 times greater for water than for gases. The osmotic pressure of water saturated with nitrous oxide at 1 atmosphere, derived from the freezing point of the gas solution, was 1.5 atmospheres. It is concluded that dissolved gases exert osmotic pressure. Partial-pressure gradients of dissolved gases in the tissues of animals and man should cause flows of water along osmotic gradients, which may partially account for some of the symptoms and signs of dysbarism.

摘要

在一个渗透计中,充满了通过2.5微米厚的聚氨酯聚醚膜与水分离的一氧化二氮饱和水,其压力在10分钟内缓慢上升8至20毫米(水柱),然后在2小时内逐渐恢复到接近零。该膜对水的渗透系数比对气体的渗透系数大约大1000倍。从气体溶液的冰点得出,在1个大气压下一氧化二氮饱和水的渗透压为1.5个大气压。得出的结论是,溶解气体施加渗透压。动物和人体组织中溶解气体的分压梯度应导致水沿渗透梯度流动,这可能部分解释了减压病的一些症状和体征。

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