新生儿和成人自然感染柯萨奇病毒时不同病毒中和性19S和7S抗体的出现时间。
Timing of different virus neutralizing 19S and 7S antibodies in natural coxsackie infections of newborn babies and adults.
作者信息
Mäkelä O, Lapinleimu K, Kostiainen E
出版信息
Clin Exp Immunol. 1968 Mar;3(3):269-76.
Abstract
Neutralizing Coxsackie antibodies arising from natural infections with Coxsackie virus type B3 or B5 were studied in adults and newborn babies. No differences could be found between the antibody response of the newborn babies and that of the adults. The antibody titres rose approximately as rapidly in the babies as in the adult patients, and the means of the peak titres did not differ significantly in the two groups. Early in the infection the neutralizing antibodies of both newborn babies and adults were exclusively IgM. There was a gradual shift to IgG in the course of 3 months, and this shift was as rapid in babies as in adults.
摘要
对因自然感染B3型或B5型柯萨奇病毒而产生的中和性柯萨奇抗体在成人和新生儿中进行了研究。新生儿和成人的抗体反应之间未发现差异。婴儿体内抗体滴度上升的速度与成年患者大致相同，两组的峰值滴度平均值无显著差异。在感染早期，新生儿和成人的中和抗体均为IgM。在3个月的过程中逐渐转变为IgG，这种转变在婴儿和成人中同样迅速。
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