Camfield P R, Metrakos K, Andermann F
Neurology. 1978 Jun;28(6):584-8. doi: 10.1212/wnl.28.6.584.
Four adolescents had basilar migraine, infrequent cerebral seizures, and severe EEG abnormalities. The clinical course was benign, with normal personality, mentation, and neurologic examination. Almost continuous EEG abnormalities, consisting of rhythmic temporo-occipital sharp and slow wave discharges, or generalized spike and wave complexes, were seen in serial recordings. The rare seizures, either focal or generalized, usually followed a migrainous aura and seemed to be readily controlled with anticonvulsant medication. The complex relationship between classical migraine and epilepsy is illustrated by this syndrome; recognition of its relatively benign course may prevent unnecessary investigation and undue alarm.
四名青少年患有基底型偏头痛、偶发性脑癫痫发作和严重的脑电图异常。临床病程呈良性，人格、精神状态和神经系统检查均正常。连续记录显示几乎持续存在脑电图异常，表现为节律性颞枕部尖波和慢波放电，或广泛性棘波和慢波复合波。罕见的癫痫发作，无论是局灶性还是全身性的，通常在偏头痛先兆之后出现，似乎很容易用抗惊厥药物控制。该综合征说明了经典偏头痛和癫痫之间的复杂关系；认识到其相对良性的病程可以避免不必要的检查和过度恐慌。
