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开普敦的脑瘫:一项为期12年的对比性回顾性研究。

Cerebral palsy in Cape Town: a comparative 12-year retrospective study.

作者信息

Arens L J, Molteno C D, Marshall S R, Robertson W I, Rabkin J

出版信息

S Afr Med J. 1978 Mar 4;53(9):319-24.

PMID:565953
Abstract

Three hundred and thirty-one Coloured and 175 White children with cerebral palsy, born between 1964 and 1975, were compared as regards aetiology and changing incidence over two 6-year periods. The following were the main points which emerged: (i) there is an apparent decrease in the total number of White children with cerebral palsy born in the second 6-year period, but for reasons discussed, there is probably little or no true decrease; (ii) there is a significant increase in the total number of Coloured cerebral palsied children born in the second 6-year period, due mainly to an increase in cases of cerebral palsy of perinatal origin, particularly cases of perinatal asphyxia; (iii) there is a high incidence of acquired cerebral palsy in both racial groups, but this is significantly higher amont the Coloured; (iv) ther is no racial difference in the incidence of cerebral palsy in babies of low birth weight; (v) both racial groups have a fairly high incidence of cerebral palsy due to kernicterus. It is interesting to speculate whether improved obstetric and neonatal care and the resultant lowering of perinatal mortality produce more handicapped babies.

摘要

对1964年至1975年间出生的331名有色人种和175名白人脑瘫患儿的病因及两个6年期间发病率的变化进行了比较。得出以下要点:(i) 在第二个6年期间出生的白人脑瘫患儿总数明显减少,但由于所讨论的原因,可能几乎没有或根本没有真正的减少;(ii) 在第二个6年期间出生的有色人种脑瘫患儿总数显著增加,主要是由于围产期脑瘫病例增加,特别是围产期窒息病例;(iii) 两个种族群体中获得性脑瘫的发病率都很高,但有色人种的发病率明显更高;(iv) 低出生体重婴儿脑瘫的发病率没有种族差异;(v) 两个种族群体中因核黄疸导致的脑瘫发病率都相当高。推测改善产科和新生儿护理以及由此导致的围产期死亡率降低是否会产生更多残疾婴儿是很有意思的。

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