Krishnamachari K A, Bhat V R, Nagarajan V, Tilak T B, Tulpule P G
Ann Nutr Aliment. 1977;31(4-6):991-6.
An outbreak of a disease characterised by jaundice, rapidly developing ascites and portal hypertension associated with 20 p. 100 mortality rate was investigated in 1974. Analysis of food samples revealed that the disease outbreak was due to the consumption of maize (corn) heavily infested with the fungus Aspergillus flavus. Unseasonal rains prior to harvest, chronic drought conditions, poor storage facilities and ignorance of dangers of consuming fungal contaminated food seem to have caused the outbreak. The level of aflatoxin in food samples consumed during the outbreak was ranging between 2.5 and 15.6 microgram/g. Anywhere between 2 and 6 mg of aflatoxin seems to have been consumed daily by the affected people for many weeks. In contrast, during 1975, analysis of corn samples from the same areas revealed very low levels of aflatoxin, viz., less than 0.1 microgram/g. This was in line with the absence of major outbreak in 1975.
1974年对一种以黄疸、迅速发展的腹水和门静脉高压为特征且死亡率达20%的疾病暴发进行了调查。对食品样本的分析表明，该疾病暴发是由于食用了被黄曲霉严重污染的玉米。收获前的异常降雨、长期干旱状况、简陋的储存设施以及对食用受真菌污染食物危险性的无知似乎导致了此次暴发。暴发期间食用的食品样本中黄曲霉毒素水平在2.5至15.6微克/克之间。受影响人群似乎连续数周每天摄入2至6毫克黄曲霉毒素。相比之下，1975年对同一地区玉米样本的分析显示黄曲霉毒素水平极低，即低于0.1微克/克。这与1975年未发生重大疾病暴发的情况相符。
