肾海藻糖酶的组织化学定位：肾小管部位的证实

Histochemical localization of renal trehalase: demonstration of a tubular site.

作者信息

Grossman I W, Sacktor B

出版信息

Science. 1968 Aug 9;161(3841):571-2. doi: 10.1126/science.161.3841.571.

DOI:10.1126/science.161.3841.571

Abstract

Trehalase activity has been localized histochemically within the cortical tubules of the human, rabbit, and mouse kidneys. The specific localization of the enzyme supports the hypothesis that trehalase, in concert with a series of other enzymes which synthesize trehalose from glucose, functions in a mechanism for the reabsorption of glucose from the glomerular filtrate.

摘要

海藻糖酶活性已通过组织化学方法定位在人、兔和小鼠肾脏的皮质小管内。该酶的特异性定位支持了这样一种假说，即海藻糖酶与一系列从葡萄糖合成海藻糖的其他酶协同作用，在从肾小球滤液中重吸收葡萄糖的机制中发挥作用。