Demelier J F, Labat J, Courtois J E
C R Acad Hebd Seances Acad Sci D. 1975 Feb 3;280(5):669-71.
Administration of trehalose by parenteral route to mammals (Guinea-pig and rabbit) equipped with Kidney trehalase is followed by rapid hydrolysis of the disaccharide which is excreted in urine only in very low amounts. When the animal under investigation has not trehalase in the kidney (rat), practically the total amount of trehalase is excreted in urine. Perfusion of kidney in rabbit confirms the very rapid hydrolysis of trehalose by this organ.
通过肠胃外途径向配备了肾脏海藻糖酶的哺乳动物(豚鼠和兔子)施用海藻糖后,二糖会迅速水解,只有极少量通过尿液排出。当被研究的动物(大鼠)肾脏中没有海藻糖酶时,几乎所有的海藻糖都会通过尿液排出。对兔子的肾脏进行灌注证实了该器官能非常迅速地水解海藻糖。