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大颗粒聚合白蛋白诱导的I型肺上皮细胞中的细胞质活性。

Cytoplasmic activity in type I pulmonary epithelial cells induced by macroaggregated albumin.

作者信息

Hapke E J, Pederson H J

出版信息

Science. 1968 Aug 9;161(3841):580-2. doi: 10.1126/science.161.3841.580.

DOI:10.1126/science.161.3841.580
PMID:5663299
Abstract

After the intravenous injection of radioalbumin macroaggregate, large numbers of cytoplasmic inclusion bodies were observed in the lung tissue of rats. The inclusions were located mainly in the cytoplasm of type I alveolar lining cells, appeared 40 minutes after the injection, and lasted up to 2 days. These observations suggest that the type I alveolar lining cells participate in the clearing mechanism of the lung tissue, a function that thus far has not been attributed to this type of cell.

摘要

静脉注射放射性白蛋白大聚合体后,在大鼠肺组织中观察到大量细胞质包涵体。这些包涵体主要位于I型肺泡衬里细胞的细胞质中,注射后40分钟出现,持续长达2天。这些观察结果表明,I型肺泡衬里细胞参与肺组织的清除机制,而迄今为止该功能尚未归因于这类细胞。

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