正常大鼠肺泡毛细血管膜及肺泡内衬物质中自体白蛋白的超微结构免疫过氧化物酶显示
Ultrastructural immunoperoxidase demonstration of autologous albumin in the alveolar capillary membrane and in the alveolar lining material in normal rats.
作者信息
Bignon J, Chahinian P, Feldmann G, Sapin C
出版信息
J Cell Biol. 1975 Feb;64(2):503-9. doi: 10.1083/jcb.64.2.503.
Abstract
The location of autologous serum albumin within the alveolar-capillary membrane was studied in the rat under physiological conditions using antialbumin antibodies labeled with peroxidase. Albumin was detected in the lung interstitium, and in numerous pinocytic vesicles within endothelial cells and type I alveolar epithelial cells. The immunoreaction was also positive at the level of plasmalemmal membranes of both cell types and in the alveolar lining material.
摘要
在生理条件下，利用过氧化物酶标记的抗白蛋白抗体，在大鼠体内研究了自体血清白蛋白在肺泡-毛细血管膜内的位置。在肺间质、内皮细胞和I型肺泡上皮细胞内的许多吞饮小泡中检测到白蛋白。在两种细胞类型的质膜水平以及肺泡内衬物质中，免疫反应也呈阳性。
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