Elefant E
Klin Padiatr. 1978 May;190(3):307-12.
Two siblings have various congenital malformations due to the teratogenic effect of anticonvulsant drugs. Their mother has a 14-year history of continuous anticonvulsant medication. The malformations noted in the older girl are less and in the 8 years younger sister more extensively developed as well as in the fetal hydantoin syndrome. The causes of different severity of the fetal hydantoin syndrome in two sisters are discussed.
两名兄弟姐妹因抗惊厥药物的致畸作用而患有各种先天性畸形。他们的母亲有14年持续服用抗惊厥药物的病史。在年长女孩身上发现的畸形较少，而在小8岁的妹妹身上，畸形发展得更广泛，与胎儿乙内酰脲综合征的情况一样。本文讨论了两姐妹中胎儿乙内酰脲综合征严重程度不同的原因。
