Veksler Ia I, Magomedova K M, Lugovets V M
Vopr Med Khim. 1978 Mar-Apr;24(2):180-4.
In a state of acute alcohol intoxication metabolic response on the stress of the central nervous system was distinctly altered in rats (formation and binding of ammonia in brain and medulla spinalis). The following effects were observed: deamidation of brain proteins was impaired, the intensity of ammonia formation was decreased, content of urea decreased and dynamics of gamma aminobutyric acid, dicarbonic amino acids and their amides was altered.
在急性酒精中毒状态下,大鼠中枢神经系统应激的代谢反应明显改变(大脑和脊髓中氨的形成与结合)。观察到以下效应:脑蛋白的脱酰胺作用受损,氨形成的强度降低,尿素含量降低,γ-氨基丁酸、二羧酸氨基酸及其酰胺的动态变化改变。