健康女性尿道的厌氧和需氧菌群
Anaerobic and aerobic urethral flora in healthy females.
作者信息
Marrie T J, Harding G K, Ronald A R
出版信息
J Clin Microbiol. 1978 Jul;8(1):67-72. doi: 10.1128/jcm.8.1.67-72.1978.
We characterized the aerobic and anaerobic urethral flora of five healthy females by performing urethral and midstream urine cultures once weekly for 8 weeks. Aerobic cultures were performed monthly for an additional 3 months. Lactobacillus spp. were isolated from 52 of 57 samples, Staphylococcus epidermidis from 42 of 57, Corynebacterium spp. from 26 of 57, and alpha-hemolytic streptococci from 14 of 57. Two subjects had E. coli serogroup O6 and group B streptococci isolated on five occasions, respectively. Anaerobes were isolated from 32 of 35 urethral urines (91%). Bacteroides melaninogenicus accounted for 46% of these isolates. The anaerobic urethral flora varied slightly from week to week, and a similar anaerobic flora was isolated from the introitus, fourchette, and cutaneous perineum. In addition, anaerobes were isolated from 16 of 18 healthy females who had a urethral urine sample cultured once only, and B. melaninogenicus was the most frequent isolate. Of the 21 B. melaninogenicus isolates identified to subspecies, 14 were subsp. intermedius.
我们通过对5名健康女性每周进行一次尿道和中段尿培养，持续8周，来对其需氧和厌氧尿道菌群进行特征分析。在接下来的3个月里，每月进行一次需氧培养。在57份样本中，有52份分离出乳酸杆菌属，42份分离出表皮葡萄球菌，26份分离出棒状杆菌属，14份分离出α-溶血性链球菌。两名受试者分别有5次分离出大肠杆菌O6血清群和B族链球菌。从35份尿道尿液中的32份（91%）分离出厌氧菌。产黑色素拟杆菌占这些分离菌的46%。厌氧尿道菌群每周略有变化，并且从阴道口、阴唇系带和会阴皮肤分离出了类似的厌氧菌群。此外，在18名仅进行过一次尿道尿液样本培养的健康女性中，有16名分离出厌氧菌，产黑色素拟杆菌是最常见的分离菌。在鉴定到亚种的21株产黑色素拟杆菌分离株中，有14株是中间亚种。
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