Teague C T, Merrill D C
Urology. 1978 May;11(5):531-5. doi: 10.1016/0090-4295(78)90179-6.
The effect of baclofen (Lioresal) and dantrolene (Dantrium) on bladder stimulation-induced detrusor-sphincter dyssynergia was studied in normal and chronic T-10 paraplegic dogs. Dantrolene, which depresses skeletal muscle contractility, had little effect on electrically evoked contractions of the urethral sphincter in dogs. Baclofen, which acts centrally by potentiating presynaptic inhibition, depressed the pudendal to pudendal nerve reflex and decreased urethral resistance during bladder stimulation.
在正常和慢性T-10截瘫犬中研究了巴氯芬（力奥来素）和丹曲林（硝苯呋海因）对膀胱刺激诱导的逼尿肌-括约肌协同失调的影响。丹曲林可抑制骨骼肌收缩力，但对犬尿道括约肌的电诱发收缩影响不大。巴氯芬通过增强突触前抑制发挥中枢作用，可抑制阴部神经至阴部神经的反射，并在膀胱刺激期间降低尿道阻力。
