[Bioptic liver changes in brucellosis (author's transl)].

Histomorphological changes of the liver are demonstrated in 120 biopsy samples of 104 patients with clinically and serologically proven Bang's disease. A granulomatous hepatitis was found in 1/3 of the patients in addition to a non-specific mobilisation of the active mesenchyma and a reactive hepatitis of changing intensity. The nodules are not looking like tuberculous granulomas, but consist of a disseminated accumulation of small lympho-histiocytic cells. Furthermore, the relatively high percentage of steatosis of the parenchyma (50%), lipofuscinosis (40%), and circumscribed hepatocellular siderosis (26%) can be considered as important lesions of parenchymal cells.