Steigleder G K
J Cutan Pathol. 1978 Apr;5(2):45-52. doi: 10.1111/j.1600-0560.1978.tb00938.x.
The majority of findings in relation to warts have been passed on from one textbook to the other since the end of the last century. More recent studies have been carried out with the electron microscope. But information is lacking as to histology, histochemistry, examination with the phase-contrast microscope, with the interference microscope, microradiography and other new techniques. Warts are a proliferation of the epidermis caused by a virus, and we know that the culprit acts in the epidermis itself. Warts are acanthomas, and a transition to malignancy is possible in predisposed persons. It is most remarkable that in the malignant tumors of epidermodysplasia verruciformis, no virus could be found. As the demonstration of viruses with the electron microscope and other techniques cannot be made as a matter of routine, we have to search for a simpler method with the light microscope. With the application of more elaborate procedures, new information about epidermal proliferation will certainly be obtained.
自上世纪末以来，大多数关于疣的研究结果都是从一本教科书传到另一本教科书。最近已经用电子显微镜进行了更多的研究。但是，关于组织学、组织化学、相差显微镜检查、干涉显微镜检查、微射线照相术和其他新技术的信息却很缺乏。疣是由病毒引起的表皮增生，我们知道病原体在表皮本身起作用。疣是棘皮瘤，在易感人群中有可能转变为恶性肿瘤。最值得注意的是，在疣状表皮发育不良的恶性肿瘤中，找不到病毒。由于用电子显微镜和其他技术常规检测病毒不太可行，我们必须在光学显微镜下寻找一种更简单的方法。通过应用更精细的程序，肯定会获得有关表皮增生的新信息。
