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接受丘脑刺激的家兔脑室脑脊液的脑电图效应

EEG effects of the ventricular cerebrospinal fluid of rabbits submitted to thalamic stimulation.

作者信息

Glatt A, Monnier M

出版信息

Pflugers Arch. 1978 Apr 25;374(1):101-4. doi: 10.1007/BF00585703.

DOI:10.1007/BF00585703
PMID:567327
Abstract

Electrical stimulation of the "somnogenic" thalamic area of Hess in chronic rabbit donors significantly increases the EEG delta activity against controls (41%; p less than or equal to 0.05). In recipient rabbits infused with cerebrospinal fluid (csf) from these donors, the delta increase against control rabbits (26%) suggests a sedative activity of the infused csf, able to counteract the waking tendency in chronic recipients.

摘要

对慢性兔供体中黑斯“促睡眠”丘脑区域进行电刺激,与对照组相比,脑电图δ活动显著增加(41%;p≤0.05)。在输注这些供体脑脊液(CSF)的受体兔中,与对照兔相比,δ活动增加(26%),表明输注的脑脊液具有镇静活性,能够抵消慢性受体兔的清醒倾向。

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本文引用的文献

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Factors in cerebrospinal fluid affecting motor activity in the rat.影响大鼠运动活动的脑脊液因素。
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Humoral transmission of sleep, V. New evidence from production of pure sleep hemodialysate.睡眠的体液传递,V. 来自纯睡眠血液透析液生产的新证据。
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Humoral transmission of sleep. IX. Activity and concentration of the sleep peptide delta in cerebral and systemic blood fractions.睡眠的体液传递。IX. 大脑和全身血液成分中睡眠肽δ的活性和浓度。
Pflugers Arch. 1975 Nov 14;360(3):225-42. doi: 10.1007/BF00583718.
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Extraction of sleep-promoting factor S from cerebrospinal fluid and from brains of sleep-deprived animals.
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The delta sleep inducing peptide (DSIP). Comparative properties of the original and synthetic nonapeptide.δ-睡眠诱导肽(DSIP)。天然与合成九肽的比较特性。
Experientia. 1977 Apr 15;33(4):548-52. doi: 10.1007/BF01922266.
7
Characterization of a delta-electroencephalogram (-sleep)-inducing peptide.一种δ-脑电图(-睡眠)诱导肽的特性分析。
Proc Natl Acad Sci U S A. 1977 Mar;74(3):1282-6. doi: 10.1073/pnas.74.3.1282.