某些潜在化疗化合物的抗分枝杆菌活性。
Antimycobacterial activity of some potential chemotherapeutic compounds.
作者信息
Damle P, McClatchy J K, Gangadharam P R, Davidson P T
出版信息
Tubercle. 1978 Jun;59(2):135-8. doi: 10.1016/0041-3879(78)90016-8.
PMID:567395
Abstract
Fourteen compounds were tested in vitro for activity against Mycobacterium intracellulare and other pathogenic mycobacteria. Only clofazimine and chaulmoogric acid showed significant activity against M. intracellulare. In view of known minimal side effects of clofazimine further studies are warranted for this drug in chemotherapy of M. intracellulare infections.
摘要
对14种化合物进行了体外测试，以检测其对细胞内分枝杆菌和其他致病性分枝杆菌的活性。只有氯法齐明和晁模酸对细胞内分枝杆菌显示出显著活性。鉴于氯法齐明已知的最小副作用，有必要对该药物用于细胞内分枝杆菌感染的化疗进行进一步研究。
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