Williamson S, Finucane E, Ellis H, Gamsu H R
Arch Dis Child. 1978 Jul;53(7):555-63. doi: 10.1136/adc.53.7.555.
Seven very low birthweight (less than 1.3 kg) preterm infants, aged between 3 and 6 weeks were fed raw, pasteurised, and boiled human milk for 3 consecutive weeks. Serial metabolic balance techniques were used to assess the absorption and retention of calcium, phosphorous, sodium, and nitrogen, and the absorption of fat. Fat absorption was reduced by approximately one-third when raw milk was heated. It is suggested that the improved fat absorption from the raw milk may be related to the preservation of milk lipases. A reduction in the amount of N retained was also noted when the infants were fed boiled milk. There were no obvious differences in the absorption of N or the absorption and retention of Ca, P, and Na between the three milks. All infants gained weight most rapidly during the week in which they were fed raw milk. The mean weight gain during this time was approximately one-third greater than that during similar periods when pasteurised or boiled milk was administered
七名极低出生体重（小于1.3千克）的早产儿，年龄在3至6周之间，连续三周分别喂食生的、巴氏杀菌的和煮沸的人乳。采用连续代谢平衡技术评估钙、磷、钠和氮的吸收与潴留，以及脂肪的吸收情况。生乳加热后脂肪吸收减少了约三分之一。提示生乳脂肪吸收改善可能与乳脂肪酶的保留有关。婴儿喂食煮沸的牛奶时，氮潴留量也有所减少。三种牛奶之间在氮的吸收或钙、磷、钠的吸收与潴留方面没有明显差异。所有婴儿在喂食生乳的那一周体重增加最快。这段时间的平均体重增加比喂食巴氏杀菌乳或煮沸乳的类似时期大约高三分之一。
