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母体剂量对乳鼠铅潴留的影响。

The effect of maternal dose on lead retention in suckling rats.

作者信息

Momcilović B

出版信息

Arch Environ Health. 1978 May-Jun;33(3):115-7. doi: 10.1080/00039896.1978.10667319.

Abstract

Lead (Pb) transfer from mother to litter was investigated at the late stage of lactation after a single intrapitoneal injection of 2.0 microgram Pb/ml marked with 203Pb. After 48 hr almost 20% of the maternal dose of 203 Pb was found in the litter, and about 0.6 and 0.2 of the injected dose was found in the liver and kidneys of suckling rats, respectively. Similar whole-body retention was observed earlier in suckling rats after a 20 times lower dose of stable lead was injected intravenously into their mothers.

摘要

在以203Pb标记的2.0微克铅/毫升进行单次腹腔注射后,于哺乳期后期研究了铅(Pb)从母体向幼崽的转移情况。48小时后,在幼崽中发现了近20%的母体203Pb剂量,在乳鼠的肝脏和肾脏中分别发现了约0.6和0.2的注射剂量。在向母鼠静脉注射低20倍剂量的稳定铅后,早期在乳鼠中观察到了类似的全身滞留情况。

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