Fine B S, Berkow J W, Fine S
Science. 1968 Oct 4;162(3849):129-30. doi: 10.1126/science.162.3849.129.
Superficial calcification was produced in the normal rabbit cornea by mild irradiation with a carbon dioxide laser. The calcification was entirely extracellular and closely resemnbled that observed in human band keratopathy, which was characterized as hydroxyapatite by x-ray diffraction. The electron-mnicroscopic appearance of calcific spheriules and conglomerates in early cornteal calcification is presented. The calcific spherules arise at the basal plasma membrane surface of the epithelial cells in close relation to their basement membrane.
通过二氧化碳激光轻度照射在正常兔角膜中产生了浅表钙化。这种钙化完全是细胞外的，与在人类带状角膜病变中观察到的钙化非常相似，通过X射线衍射其特征为羟基磷灰石。本文展示了早期角膜钙化中钙化球和聚集体的电子显微镜外观。钙化球出现在上皮细胞基底质膜表面，与它们的基底膜密切相关。
