低剂量麻疹疫苗接种
Measles vaccination with reduced dosage.
作者信息
Hendrickse R G, Montefiore D
出版信息
Br Med J. 1968 Oct 5;4(5622):28-30. doi: 10.1136/bmj.4.5622.28.
Abstract
A field trial is reported in which good sero-conversion rates were obtained when a dose of 200 TCID(50) Beckenham 31 strain (Wellcovax) measles vaccine was administered by Ped-O-Jet subcutaneously in a volume of 0.5 ml. per dose. It is suggested that use of this reduced dosage would lead to a significant reduction in the cost per dose of the vaccine, especially when administered on a scale large enough to justify the use of multidose containers.
摘要
本文报道了一项现场试验，当使用Ped - O - Jet皮下注射0.5毫升/剂量的200个半数组织培养感染剂量（TCID50）的贝肯纳姆31株（Wellcovax）麻疹疫苗时，获得了良好的血清转化率。有人认为，使用这种减少后的剂量将导致每剂疫苗成本显著降低，特别是当大规模使用足以证明使用多剂量容器合理时。
相似文献
1
Measles vaccination with reduced dosage.
Br Med J. 1968 Oct 5;4(5622):28-30. doi: 10.1136/bmj.4.5622.28.
2
Problems of future measles vaccination in developing countries.
Trans R Soc Trop Med Hyg. 1975;69(1):31-5. doi: 10.1016/0035-9203(75)90007-3.
3
Measles vaccination in Zaïre--when and how?
Trans R Soc Trop Med Hyg. 1980;74(3):381-2. doi: 10.1016/0035-9203(80)90105-4.
4
Trial of a reduced dose of measles vaccine in Nigerian children.
Bull World Health Organ. 1976;53(4):361-4.
5
Two studies on optimal timing for measles vaccination.
Hum Vaccin Immunother. 2013 Dec;9(12):2499. doi: 10.4161/hv.27467. Epub 2013 Dec 1.
6
Evaluation of methods designed to reduce cost of measles vaccine programmes.
Trans R Soc Trop Med Hyg. 1975;69(1):26-8. doi: 10.1016/0035-9203(75)90005-x.
7
Seroconversion after measles vaccination at nine and fifteen months of age.
Pediatr Infect Dis J. 2003 Aug;22(8):691-5. doi: 10.1097/01.inf.0000078158.23337.ed.
8
Outbreaks spur measles vaccine studies.
JAMA. 2011 Dec 14;306(22):2440-2. doi: 10.1001/jama.2011.1756.
9
[Field trial of attenuated measles vaccine].
Turk Hij Tecr Biyol Derg (1961). 1967;27(2-3):137-50.
10
Vindication of policy of vitamin A with measles vaccination.
Lancet. 1997 Jul 12;350(9071):81-2. doi: 10.1016/S0140-6736(05)61809-0.
引用本文的文献
1
Trial of a reduced dose of measles vaccine in Nigerian children.
Bull World Health Organ. 1976;53(4):361-4.
本文引用的文献
1
Viral content and stability of live measles vaccines.
Am J Dis Child. 1962 Mar;103:437-40. doi: 10.1001/archpedi.1962.02080020449059.
2
Measles vaccine.
JAMA. 1961 Aug 26;177:537-41. doi: 10.1001/jama.1961.03040340001001.
3
Comparative trial of further attenuated measles vaccines.
Br Med J. 1966 Mar 26;1(5490):779-81. doi: 10.1136/bmj.1.5490.779.
4
Attenuated measles virus vaccine dosage study--Cleveland, Ohio, 1966.
Am J Epidemiol. 1968 Jan;87(1):247-53. doi: 10.1093/oxfordjournals.aje.a120806.
5
[Vaccination against measles in a rural Senegalese environment with superattenuated live vaccine (Schwarz) by means of an injector without a needle (Dermojet). Possibilities of combination with vaccine].
Bull Soc Med Afr Noire Lang Fr. 1965;10(3):392-406.
6
Administration of measles vaccine by dermojet.
Lancet. 1966 May 14;1(7446):1076-7. doi: 10.1016/s0140-6736(66)91015-4.
Zotero 插件