• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

o,p'-滴滴涕在哺乳动物子宫和鸟类输卵管中的雌激素活性。

Estrogenic activity of o,p'-DDT in the mammalian uterus and avian oviduct.

作者信息

Bitman J, Cecil H C, Harris S J, Fries G F

出版信息

Science. 1968 Oct 18;162(3851):371-2. doi: 10.1126/science.162.3851.371.

DOI:10.1126/science.162.3851.371
PMID:5677532
Abstract

When rats and birds were treated with o, p-DDT, their reproductive tissues exhibited the same response as when they were treated with estrogen. Weight, water content, glycogen, and RNA increased in uteri and oviducts of rats, chickens, and quail receiving o, p-DDT; p, p-DDT produced little if any response. The o, p-DDT did not accumulate in the reproductive or adipose tissues to a greater extent than p, p-DDT.

摘要

当用邻,对 - 滴滴涕处理大鼠和鸟类时,它们的生殖组织表现出与用雌激素处理时相同的反应。接受邻,对 - 滴滴涕处理的大鼠、鸡和鹌鹑的子宫和输卵管的重量、含水量、糖原和核糖核酸增加;而对,对 - 滴滴涕几乎没有产生任何反应。邻,对 - 滴滴涕在生殖组织或脂肪组织中的积累程度并不比 对,对 - 滴滴涕更大。

相似文献

1
Estrogenic activity of o,p'-DDT in the mammalian uterus and avian oviduct.o,p'-滴滴涕在哺乳动物子宫和鸟类输卵管中的雌激素活性。
Science. 1968 Oct 18;162(3851):371-2. doi: 10.1126/science.162.3851.371.
2
Differing estrogenic activities for the enantiomers of o, p'-DDT in immature female rats.邻,对'-滴滴涕对映体在未成熟雌性大鼠中的雌激素活性差异。
Can J Physiol Pharmacol. 1976 Aug;54(4):629-32. doi: 10.1139/y76-088.
3
Avian eggshell thinning caused by transovarian exposure to o,p'-DDT: changes in histology and calcium-binding protein production in the oviduct uterus.经卵传递暴露于 o,p'-DDT 导致禽类蛋壳变薄:输卵管子宫组织学和钙结合蛋白产生的变化。
J Toxicol Sci. 2020;45(3):131-136. doi: 10.2131/jts.45.131.
4
Reproductive and developmental effects of transovarian exposure to o,p'-DDT in Japanese quails.经卵巢暴露于邻对滴滴涕对日本鹌鹑生殖和发育的影响。
Environ Toxicol Chem. 2009 Apr;28(4):782-90. doi: 10.1897/08-218R.1.
5
The estrogenic activity of DDT: the in vitro induction of an estrogen-inducible protein by o,p'-DDT.滴滴涕的雌激素活性:邻,对'-滴滴涕对雌激素诱导蛋白的体外诱导作用。
Toxicol Appl Pharmacol. 1984 Dec;76(3):537-43. doi: 10.1016/0041-008x(84)90358-2.
6
Estrogenicity of o,p'-DDT in rats.大鼠体内邻,对'-滴滴涕的雌激素活性
J Agric Food Chem. 1971 Jan-Feb;19(1):61-5. doi: 10.1021/jf60173a049.
7
The levo enantiomer of o,p'-DDT inhibits the binding of 17 beta-estradiol to the estrogen receptor.
Life Sci. 1987 Jan 12;40(2):215-21. doi: 10.1016/0024-3205(87)90361-4.
8
The estrogenic activity of DDT: in vivo and in vitro induction of a specific estrogen inducible uterine protein by o,p'-DDT.滴滴涕的雌激素活性:体内和体外实验中o,p'-滴滴涕对一种特定雌激素诱导性子宫蛋白的诱导作用
Life Sci. 1980 Sep 22;27(12):1111-7. doi: 10.1016/0024-3205(80)90037-5.
9
Effects of transovarian exposure to p,p'-DDT and p,p'-DDE on avian reproduction using Japanese quails.通过日本鹌鹑经卵巢暴露于对,对'-滴滴涕和对,对'-滴滴伊对鸟类繁殖的影响。
J Toxicol Sci. 2013;38(6):903-12. doi: 10.2131/jts.38.903.
10
Xenobiotics released from fat during fasting produce estrogenic effects in ovariectomized mice.禁食期间从脂肪中释放的外源性化学物质在去卵巢小鼠中产生雌激素样作用。
Cancer Res. 1997 Mar 1;57(5):865-9.

引用本文的文献

1
The Association between Long-Term DDT or DDE Exposures and an Altered Sperm Epigenome-a Cross-Sectional Study of Greenlandic Inuit and South African VhaVenda Men.长期接触滴滴涕或滴滴伊与精子表观基因组改变的关联:格陵兰因纽特人和南非 VhaVenda 男性的横断面研究。
Environ Health Perspect. 2024 Jan;132(1):17008. doi: 10.1289/EHP12013. Epub 2024 Jan 31.
2
Exposure to Endocrine Disrupting Chemicals and Risk of Breast Cancer.内分泌干扰化学物质暴露与乳腺癌风险。
Int J Mol Sci. 2020 Nov 30;21(23):9139. doi: 10.3390/ijms21239139.
3
Agrochemicals with estrogenic endocrine disrupting properties: Lessons Learned?
具有雌激素内分泌干扰特性的农用化学品:得到教训了吗?
Mol Cell Endocrinol. 2020 Dec 1;518:110860. doi: 10.1016/j.mce.2020.110860. Epub 2020 May 12.
4
Associations between prenatal exposure to DDT and DDE and allergy symptoms and diagnoses in the Venda Health Examination of Mothers, Babies and their Environment (VHEMBE), South Africa.南非文达母婴及其环境健康检查(VHEMBE)中产前接触滴滴涕和滴滴伊与过敏症状和诊断之间的关联。
Environ Res. 2020 Jun;185:109366. doi: 10.1016/j.envres.2020.109366. Epub 2020 Mar 15.
5
The Disappearing Sperms: Analysis of Reports Published Between 1980 and 2015.消失的精子:1980年至2015年间发表报告的分析
Am J Mens Health. 2017 Jul;11(4):1279-1304. doi: 10.1177/1557988316643383. Epub 2016 Apr 19.
6
Cell-based assays for screening androgen receptor ligands.用于筛选雄激素受体配体的基于细胞的检测方法。
Semin Reprod Med. 2015 May;33(3):225-34. doi: 10.1055/s-0035-1552989. Epub 2015 Jun 2.
7
Exogenous hormonal regulation in breast cancer cells by phytoestrogens and endocrine disruptors.植物雌激素和内分泌干扰物对乳腺癌细胞的外源性激素调节。
Curr Med Chem. 2014;21(9):1129-45. doi: 10.2174/09298673113206660291.
8
The effect of o,p'-DDT on Japanese quail.邻,对-滴滴涕对日本鹌鹑的影响。
Bull Environ Contam Toxicol. 1970 Mar;5(2):152-7. doi: 10.1007/BF01617193.
9
Tests of estrogenicity in rats fed low levels of o,p'DDT.
Bull Environ Contam Toxicol. 1970 Jan;5(1):61-6. doi: 10.1007/BF01545127.
10
Current progress in the determination of the polychlorinated biphenyls.多氯联苯测定的当前进展。
Bull Environ Contam Toxicol. 1969 Jul;4(4):192-201. doi: 10.1007/BF01557977.