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失忆症:足部电击与电惊厥休克的时间关系的一种作用。

Amnesia: a function of the temporal relation of footshock to electroconvulsive shock.

作者信息

Schneider A M, Sherman W

出版信息

Science. 1968 Jan 12;159(3811):219-21. doi: 10.1126/science.159.3811.219.

DOI:10.1126/science.159.3811.219
PMID:5688702
Abstract

When rats received a brief footshock upon stepping off an elevated platform, and an electroconvulsive shock 30 seconds or 6 hours afterward, amnesia was not observed 24 hours later. If a second footshock (noncontingent) was delivered 0.5 second before the electroconvulsive shock, amnesia was observed. The amnesia was temporary if conditioning was strong and permanent if conditioning was weak.

摘要

当大鼠从高架平台上跳下时受到短暂的足部电击,并在30秒或6小时后接受电惊厥休克,24小时后未观察到失忆现象。如果在电惊厥休克前0.5秒给予第二次足部电击(非条件性),则会观察到失忆现象。如果条件反射强烈,失忆是暂时的;如果条件反射较弱,失忆则是永久性的。

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