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6%羟乙基淀粉、45%右旋糖酐60和5.5%氧化聚明胶对人体志愿者血容量及循环的影响(作者译)

[The effect of 6% hydroxyethyl starch, 45% dextran 60 and 5.5% oxy-poly-gelatine on blood volume and circulation in human volunteers (author's transl)].

作者信息

Kilian J, Spilker D, Borst R

出版信息

Anaesthesist. 1975 May;24(5):193-7.

PMID:56898
Abstract

Studies in 30 volunteers showed that the volume increasing effect of a 2.5% Oxypolygelatine-solution is rather short (90 to 240 min), whereas the volume effect of a 4.5% Dextran 60 solution remained stable over a period of 240 min hydroxethyl-starch solution 6% caused a distinct increase in blood volume after a period of 90 min and of 240 min in five volunteers, while the blood volume of the other volunteers remained rather constant. The parameters we measured provide no explanation for this effect.

摘要

对30名志愿者的研究表明,2.5%氧化聚明胶溶液的扩容效果相当短暂(90至240分钟),而4.5%右旋糖酐60溶液的扩容效果在240分钟内保持稳定。6%羟乙基淀粉溶液在90分钟后使五名志愿者的血容量明显增加,240分钟后也是如此,而其他志愿者的血容量则保持相当稳定。我们测量的参数无法解释这种效应。

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