羟乙基淀粉对血液凝固的影响（作者译）

[The influence of hydroxyethyl starch on blood clotting (author's transl)].

作者信息

Peter K, Gander H P, Lutz H, Nold W, Stosiek U

出版信息

Anaesthesist. 1975 May;24(5):219-24.

PMID:56903

Abstract

It has been shown in clinical experiments that blood coagulation was delayed by Dextran 60 and Hydroxyethylstarch (HAS). During the postoperative period up to the 2nd postoperative day the measured clotting factors were decreased within the physiological range. Platelet adhesiveness was mainly reduced in the group of Dextran 60 and in the male Hydroxyethylstarch group. A similar effect of haemodilution as seen by haematocrit and blood viscosity results was produced by Dextran 60 and Hydroxyethylstarch. In the electrolyte group the values obtained did not show any significant influence on blood coagulation apart from a light and temporary trend to hypercoagulation during the day of operation.

摘要

临床实验表明，右旋糖酐60和羟乙基淀粉（HAS）会延迟血液凝固。在术后直至术后第2天的期间内，所测凝血因子在生理范围内有所下降。血小板黏附性主要在右旋糖酐60组和男性羟乙基淀粉组中降低。右旋糖酐60和羟乙基淀粉产生了与血细胞比容和血液黏度结果所见类似的血液稀释作用。在电解质组中，除了手术当天有轻微且暂时的高凝趋势外，所获数值对血液凝固未显示出任何显著影响。

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