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[不同血浆代用品在等容血液稀释中对血液凝固的影响(作者译)]

[The influence of different plasma substitutes on blood clotting in isovolaemic haemodilution (author's transl)].

作者信息

Martin E, Armbruster I, Fischer E, Kraatz J, Kersting K H, Oberst R, Peter K

出版信息

Anaesthesist. 1976 Apr;25(4):181-4.

PMID:58563
Abstract

In a clinical study, the influence of 6 per cent Dextran 60 and 6 per cent hydroxyethyl starch (HES) on blood clotting was measured in 2 comparable groups of surgical patients. Haematocrit, platelets, thromboplastin time according to Quick, partial thromboplastin time and fibrinogen level were determined before and after isovolaemic haemodilution, and subsequently during a period of 14 days. There was no significant difference between the diluents with regard to their effect on blood clotting. Changes within each group may be ascribed to the diluting effect of the plasma substitutes.

摘要

在一项临床研究中,在两组具有可比性的外科手术患者中,测定了6%的右旋糖酐60和6%的羟乙基淀粉(HES)对血液凝固的影响。在等容血液稀释前后以及随后的14天内,测定了血细胞比容、血小板、根据Quick法测定的凝血酶原时间、部分凝血活酶时间和纤维蛋白原水平。两种稀释剂对血液凝固的影响没有显著差异。每组内的变化可能归因于血浆代用品的稀释作用。

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