细胞黏菌对趋化因子叶酸的失活作用及反应产物的鉴定
Inactivation of the chemoattractant folic acid by cellular slime molds and identification of the reaction product.
作者信息
Pan P, Wurster B
出版信息
J Bacteriol. 1978 Dec;136(3):955-9. doi: 10.1128/jb.136.3.955-959.1978.
Abstract
Enzymes inactivating the chemoattractants folic acid and pterin were detected in extracellular, intracellular, and particulate fractions obtained from Dictyostelium discoideum strains NC4 and AX-2 and Polysphondylium violaceum. The products of the inactivation reaction were analyzed by thin-layer chromatography and UV spectroscopy. Results obtained indicate that folic acid and pterin were deaminated to 2-deamino folic acid and lumazine, respectively.
摘要
在从盘基网柄菌NC4和AX - 2菌株以及紫多头绒泡菌中获得的细胞外、细胞内和颗粒组分中检测到了使趋化因子叶酸和蝶呤失活的酶。通过薄层色谱法和紫外光谱法分析了失活反应的产物。所得结果表明，叶酸和蝶呤分别被脱氨基生成2 - 脱氨基叶酸和核黄素。
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