Solomon J B
Immunology. 1968 Aug;15(2):219-26.
The bactericidal activity of chicken serum before and after injection of 1–35-day-old chickens with has been studied. The bactericidal action of immune serum is temperature-dependent. Treatment of both normal and immune serum with mercaptoethanol, by heating to 56°, produced a ten-fold reduction in bactericidal activity. The ingested yolk contained bactericidal factors at 1 day of age. Bactericidal activity of normal serum declined very slowly during the first 5 weeks of development. Bactericidal activity released by injection of , showed some specificity for the somatic-O antigens and a high degree of species specificity. Injection of into 1-day-old chicks resulted in the rapid release of a high level of bactericidal activity into the circulation. The bactericidal antibody response to an injection of increased from 4 to 35 days of development. In chickens of 3 weeks of age, or older, induced bactericidal antibody remained at a high level for several weeks.
研究了给1至35日龄雏鸡注射[具体物质未提及]前后鸡血清的杀菌活性。免疫血清的杀菌作用取决于温度。用巯基乙醇处理正常血清和免疫血清，加热至56°，杀菌活性降低了十倍。雏鸡1日龄时摄入的蛋黄含有杀菌因子。正常血清的杀菌活性在发育的前5周下降非常缓慢。注射[具体物质未提及]释放的杀菌活性对菌体O抗原表现出一定特异性和高度的种属特异性。给1日龄雏鸡注射[具体物质未提及]导致循环中迅速释放高水平的杀菌活性。对注射[具体物质未提及]的杀菌抗体反应在发育的4至35天增加。在3周龄及以上的鸡中，诱导产生的杀菌抗体在数周内保持在高水平。
